Delequamine

Base Information

Chemical Name:Delequamine
CAS No.:119905-05-4
Molecular Formula:C₁₈H₂₆N₂O₃S
Molecular Weight:350.482
Hs Code.:
Mol file:119905-05-4.mol

Synonyms:6H-Isoquino[2,1-g][1,6]naphthyridine,5,8,8a,9,10,11,12,12a,13,13a-decahydro-3-methoxy-12-(methylsulfonyl)-, [8aR-(8aa,12aa,13aa)]-; Delequamine

Suppliers and Price of Delequamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
DELEQUAMINE 95.00%
5MG
$ 500.91

Total 1 raw suppliers

Chemical Property of Delequamine

Chemical Property:

PSA：58.23000
LogP:2.99490

Purity/Quality:: DELEQUAMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Impotence therapy adjunct.

Technology Process of Delequamine

There total 26 articles about Delequamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 14446-29-8
6-Methoxy-3,4-dihydroisoquinoline

: 119813-87-5,119905-05-4,121961-55-5,129214-09-1,131346-52-6,131346-53-7
(8aα,12aα,13aα)-5,8,8a,9,10,11,12,12a,13,13a-decahydro-3-methoxy-12-(methylsulfonyl)-6H-isoquino<2,1-g><1,6>naphthyridine

Guidance literature:: Multi-step reaction with 4 steps

1: 78 percent / LDA / tetrahydrofuran / -40 °C

2: 60 percent / H₂ / Rh-Al₂O₃ / acetic acid

3: LiAlH₄ / tetrahydrofuran

4: NEt₃ / CH₂Cl₂

With lithium aluminium tetrahydride; hydrogen; triethylamine; lithium diisopropyl amide; rhodium on alumina; In tetrahydrofuran; dichloromethane; acetic acid;
DOI:10.1021/jm00129a002

Reference yield:

: 60511-47-9
2-methylnicotinic acid diethylamide

: 119813-87-5,119905-05-4,121961-55-5,129214-09-1,131346-52-6,131346-53-7
(8aα,12aα,13aα)-5,8,8a,9,10,11,12,12a,13,13a-decahydro-3-methoxy-12-(methylsulfonyl)-6H-isoquino<2,1-g><1,6>naphthyridine

Guidance literature:: Multi-step reaction with 4 steps

1: 78 percent / LDA / tetrahydrofuran / -40 °C

2: 60 percent / H₂ / Rh-Al₂O₃ / acetic acid

3: LiAlH₄ / tetrahydrofuran

4: NEt₃ / CH₂Cl₂

With lithium aluminium tetrahydride; hydrogen; triethylamine; lithium diisopropyl amide; rhodium on alumina; In tetrahydrofuran; dichloromethane; acetic acid;
DOI:10.1021/jm00129a002

Reference yield:

: 119813-94-4
5,8,13,13a-tetrahydro-3-methoxy-8-oxo-6H-isoquino<2,1-g><1,6>naphthyridine

: 119813-87-5,119905-05-4,121961-55-5,129214-09-1,131346-52-6,131346-53-7
(8aα,12aα,13aα)-5,8,8a,9,10,11,12,12a,13,13a-decahydro-3-methoxy-12-(methylsulfonyl)-6H-isoquino<2,1-g><1,6>naphthyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 60 percent / H₂ / Rh-Al₂O₃ / acetic acid

2: LiAlH₄ / tetrahydrofuran

3: NEt₃ / CH₂Cl₂

With lithium aluminium tetrahydride; hydrogen; triethylamine; rhodium on alumina; In tetrahydrofuran; dichloromethane; acetic acid;
DOI:10.1021/jm00129a002