8-chloro-6-(2-fluoro-phenyl)-1-methyl-5-nitroso-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine

Base Information

Chemical Name:8-chloro-6-(2-fluoro-phenyl)-1-methyl-5-nitroso-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine
CAS No.:59469-02-2
Molecular Formula:C₁₈H₁₄ClFN₄O
Molecular Weight:356.787
Hs Code.:

8-chloro-6-(2-fluoro-phenyl)-1-methyl-5-nitroso-5,6-dihydro-4<i>H</i>-benzo[<i>f</i>]imidazo[1,5-<i>a</i>][1,4]diazepine

Synonyms:8-chloro-6-(2-fluoro-phenyl)-1-methyl-5-nitroso-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine

Suppliers and Price of 8-chloro-6-(2-fluoro-phenyl)-1-methyl-5-nitroso-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 8-chloro-6-(2-fluoro-phenyl)-1-methyl-5-nitroso-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine

Chemical Property:

Purity/Quality:: 95%+ or 98%+ ^*data from raw suppliers

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Hazard Codes:

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Technology Process of 8-chloro-6-(2-fluoro-phenyl)-1-methyl-5-nitroso-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine

There total 11 articles about 8-chloro-6-(2-fluoro-phenyl)-1-methyl-5-nitroso-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 59468-07-4
8-chloro-6-(2-fluorophenyl)-5,6-dihydro-1-methyl-6H-imidazo<1,5-a><1,4>benzodiazepine

: 59469-02-2
8-chloro-6-(2-fluoro-phenyl)-1-methyl-5-nitroso-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine

Guidance literature:: With potassium hydroxide; sodium nitrite; In acetic acid;

Reference yield:

: 7-chloro-1,3-dihydro-5-(2-fluorophenyl)-2-(1-nitromethylene)-2H-1,4-benzodiazepine 4-oxide

: 59469-02-2
8-chloro-6-(2-fluoro-phenyl)-1-methyl-5-nitroso-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine

Guidance literature:: Multi-step reaction with 6 steps

1: aluminum nickel / tetrahydrofuran; methanol

2: PPA; acetic anhydride / methanol; dichloromethane; water

3: hydrogen / dichloromethane; water; acetic acid; Petroleum ether

4: manganese dioxide / toluene

5: zinc / dichloromethane; water; acetic acid

6: potassium hydroxide; sodium nitrite / acetic acid

With potassium hydroxide; PPA; manganese dioxide; hydrogen; acetic anhydride; zinc; sodium nitrite; aluminum nickel; In tetrahydrofuran; methanol; dichloromethane; water; acetic acid; toluene; Petroleum ether;

Reference yield:

: 59469-74-8
8-chloro-6-(2-fluorophenyl)-1-methyl-6H-imidazo<1,5-a><1,4>benzodiazepine

: 59469-02-2
8-chloro-6-(2-fluoro-phenyl)-1-methyl-5-nitroso-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine

Guidance literature:: Multi-step reaction with 3 steps

1: N-methyl-acetamide; acetic acid; ethyl acetate

2: zinc / dichloromethane; water; acetic acid

3: potassium hydroxide; sodium nitrite / acetic acid

With potassium hydroxide; zinc; sodium nitrite; In N-methyl-acetamide; dichloromethane; water; acetic acid; ethyl acetate;