1-methyl>-4--4-ethyl-3-methyl-2-pyrryl>methyl>benzene

Base Information

• Chemical Name: 1-methyl>-4--4-ethyl-3-methyl-2-pyrryl>methyl>benzene
• CAS No.: 144629-78-7
• Molecular Formula: C₅₆H₆₂N₄O₈
• Molecular Weight: 919.13
• Mol file: 144629-78-7.mol

Synonyms:1-methyl>-4--4-ethyl-3-methyl-2-pyrryl>methyl>benzene

Chemical Property of 1-methyl>-4--4-ethyl-3-methyl-2-pyrryl>methyl>benzene

Chemical Property:

Purity/Quality:

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Technology Process of 1-methyl>-4--4-ethyl-3-methyl-2-pyrryl>methyl>benzene

There total 5 articles about 1-methyl>-4--4-ethyl-3-methyl-2-pyrryl>methyl>benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

2-(ethyloxycarbonyl)-3-ethyl-4-methylpyrrole (4949-58-0) + dibenzyl 5-(4-formylphenyl)-2,3,7,8-tetramethyldipyrromethane-1,9-dicarboxylate (144629-80-1) → 1-methyl>-4--4-ethyl-3-methyl-2-pyrryl>methyl>benzene (144629-78-7)

Guidance literature:

With toluene-4-sulfonic acid; In ethanol; for 2h; Heating;

DOI:10.1021/ja9541138

Reference yield:

4-(hydroxymethyl)benzaldehyde diethyl acetal (125734-44-3) → 1-methyl>-4--4-ethyl-3-methyl-2-pyrryl>methyl>benzene (144629-78-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 75 percent / TsOH / ethanol / 3 h / Heating

2: 85 percent / tetrapropylammonium perruthenate (TPAP), 4-methylmorpholine N-oxide (NMO) / CH₂Cl₂ / 2 h / Ambient temperature

3: 88 percent / TsOH / ethanol / 2 h / Heating

With tetrapropylammonium perruthennate; toluene-4-sulfonic acid; 4-methylmorpholine N-oxide; In ethanol; dichloromethane;

DOI:10.1021/ja9541138

Reference yield:

dibenzyl 5-<4-(hydroxymethyl)phenyl>-2,3,7,8-tetramethyldipyrromethane-1,9-dicarboxylate (144629-79-8) → 1-methyl>-4--4-ethyl-3-methyl-2-pyrryl>methyl>benzene (144629-78-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / tetrapropylammonium perruthenate (TPAP), 4-methylmorpholine N-oxide (NMO) / CH₂Cl₂ / 2 h / Ambient temperature

2: 88 percent / TsOH / ethanol / 2 h / Heating

With tetrapropylammonium perruthennate; toluene-4-sulfonic acid; 4-methylmorpholine N-oxide; In ethanol; dichloromethane;

DOI:10.1021/ja9541138

upstream raw materials:

2-(ethyloxycarbonyl)-3-ethyl-4-methylpyrrole

dibenzyl 5-(4-formylphenyl)-2,3,7,8-tetramethyldipyrromethane-1,9-dicarboxylate

4-(hydroxymethyl)benzaldehyde diethyl acetal

3,4-dimethyl-pyrrole-2-carboxylic acid benzyl ester

Downstream raw materials:

C₄₂H₅₀N₄O₈

5,15-Bis(2,5-dimethoxyphenyl)-2,8,12,18-tetraethyl-3,7,13,17-tetramethylporphin