4-CHLOROBENZYLSULFONYLACETIC ACID

Base Information

• Chemical Name: 4-CHLOROBENZYLSULFONYLACETIC ACID
• CAS No.: 118672-20-1
• Molecular Formula: C9H9 Cl O4 S
• Molecular Weight: 248.687
• Hs Code.: 2916399090
• Mol file: 118672-20-1.mol

Synonyms:Aceticacid, [[(4-chlorophenyl)methyl]sulfonyl]- (9CI);2-(4-Chlorobenzylsulfonyl)acetic acid; 4-Chlorobenzylsulfonylacetic acid; NSC190485

Chemical Property of 4-CHLOROBENZYLSULFONYLACETIC ACID

Chemical Property:

• Vapor Pressure: 2.04E-11mmHg at 25°C
• Melting Point: 151.5-152.5 °C
• Refractive Index: 1.587
• Boiling Point: 514.7°C at 760 mmHg
• PKA: 2.46±0.10(Predicted)
• Flash Point: 265.1°C
• PSA: 79.82000
• Density: 1.494g/cm³
• LogP: 2.42020

Purity/Quality:

>97% ^*data from raw suppliers

[(4-Chlorobenzyl)sulfonyl]aceticAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-CHLOROBENZYLSULFONYLACETIC ACID

There total 5 articles about 4-CHLOROBENZYLSULFONYLACETIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2-(((4-chlorobenzyl-2-yl)mercapto))acetic acid (90649-82-4) → 2-(((4-chlorobenzyl)sulfonyl))acetic acid (118672-20-1)

Guidance literature:

With dihydrogen peroxide; acetic acid; Reflux;

DOI:10.1039/c7md00017k

Reference yield: 82.1%

→ 2-(((4-chlorobenzyl)sulfonyl))acetic acid (118672-20-1)

Guidance literature:

With dihydrogen peroxide; acetic acid; at 20 ℃;

Reference yield:

(4-chlorophenyl)methanethiol (6258-66-8) → 2-(((4-chlorobenzyl)sulfonyl))acetic acid (118672-20-1)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous NaOH

2: acetic acid anhydride; glacial acetic acid; aqueous H₂O₂

With sodium hydroxide; dihydrogen peroxide; acetic anhydride; acetic acid;

DOI:10.1021/ja01195a604

upstream raw materials:

2-(((4-chlorobenzyl-2-yl)mercapto))acetic acid

(4-chlorophenyl)methanethiol

4-chlorobenzyl bromide

1-Chloro-4-(chloromethyl)benzene

Downstream raw materials:

4-Chlorbenzyl-jodmethyl-sulfon

4-Chlorbenzyl-dijodmethyl-sulfon

N-(2-chloro-ethyl)-2-(4-chloro-phenylmethanesulfonyl)-acetamide

2-(4-chloro-phenylmethanesulfonyl)-N-(2-hydroxy-ethyl)-acetamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 118672-20-1 4-CHLOROBENZYLSULFONYLACETIC ACID

Send

Send

Metric Ton KG G Pound L ML

Send

Send