N-(2-(methylsulfonyl)benzyl)-2-(1-(di-tert-butoxycarbonylamino)isoquinolin-6-ylamino)-2-(3-propylphenyl)acetamide

Base Information

• Chemical Name: N-(2-(methylsulfonyl)benzyl)-2-(1-(di-tert-butoxycarbonylamino)isoquinolin-6-ylamino)-2-(3-propylphenyl)acetamide
• CAS No.: 918811-33-3
• Molecular Formula: C₃₈H₄₆N₄O₇S
• Molecular Weight: 702.872
• Mol file: 918811-33-3.mol

Synonyms:N-(2-(methylsulfonyl)benzyl)-2-(1-(di-tert-butoxycarbonylamino)isoquinolin-6-ylamino)-2-(3-propylphenyl)acetamide

Chemical Property of N-(2-(methylsulfonyl)benzyl)-2-(1-(di-tert-butoxycarbonylamino)isoquinolin-6-ylamino)-2-(3-propylphenyl)acetamide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N-(2-(methylsulfonyl)benzyl)-2-(1-(di-tert-butoxycarbonylamino)isoquinolin-6-ylamino)-2-(3-propylphenyl)acetamide

There total 1 articles about N-(2-(methylsulfonyl)benzyl)-2-(1-(di-tert-butoxycarbonylamino)isoquinolin-6-ylamino)-2-(3-propylphenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(2-(methylsulfonyl)benzyl)-2-(1-(di-tert-butoxycarbonylamino)isoquinolin-6-ylamino)-2-(3-allylphenyl)acetamide (918811-32-2) → N-(2-(methylsulfonyl)benzyl)-2-(1-(di-tert-butoxycarbonylamino)isoquinolin-6-ylamino)-2-(3-propylphenyl)acetamide (918811-33-3)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In methanol; for 1.2h; under 3102.97 Torr;

Reference yield:

N-(2-(methylsulfonyl)benzyl)-2-(1-(di-tert-butoxycarbonylamino)isoquinolin-6-ylamino)-2-(3-propylphenyl)acetamide (918811-33-3) → N-(2-(methylsulfonyl)benzyl)-2-(1-aminoisoquinolin-6-ylamino)-2-(3-propylphenyl)acetamide trifluoroacetate

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; ethyl acetate; at 20 ℃;

upstream raw materials:

N-(2-(methylsulfonyl)benzyl)-2-(1-(di-tert-butoxycarbonylamino)isoquinolin-6-ylamino)-2-(3-allylphenyl)acetamide