(+)-<2'R,6R,7R>-6-methyl-7-(6-methylhept-2-yl)-2-(phenylsulfonyl)bicyclo<4.3.0>-1-nonene

Base Information

• Chemical Name: (+)-<2'R,6R,7R>-6-methyl-7-(6-methylhept-2-yl)-2-(phenylsulfonyl)bicyclo<4.3.0>-1-nonene
• CAS No.: 156137-92-7
• Molecular Formula: C₂₄H₃₆O₂S
• Molecular Weight: 388.615
• Mol file: 156137-92-7.mol

Synonyms:(+)-<2'R,6R,7R>-6-methyl-7-(6-methylhept-2-yl)-2-(phenylsulfonyl)bicyclo<4.3.0>-1-nonene

Chemical Property of (+)-<2'R,6R,7R>-6-methyl-7-(6-methylhept-2-yl)-2-(phenylsulfonyl)bicyclo<4.3.0>-1-nonene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+)-<2'R,6R,7R>-6-methyl-7-(6-methylhept-2-yl)-2-(phenylsulfonyl)bicyclo<4.3.0>-1-nonene

There total 5 articles about (+)-<2'R,6R,7R>-6-methyl-7-(6-methylhept-2-yl)-2-(phenylsulfonyl)bicyclo<4.3.0>-1-nonene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(+)-<2'R,6R,7R>-6-methyl-7-(6-methylhept-2-yl)-2-(phenylsulfonyl)bicyclo<4.3.0>-1,4-nonadiene (152459-05-7) → (+)-<2'R,6R,7R>-6-methyl-7-(6-methylhept-2-yl)-2-(phenylsulfonyl)bicyclo<4.3.0>-1-nonene (156137-92-7)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethyl acetate; for 16h;

DOI:10.1016/0040-4020(96)00147-0

Reference yield:

(3R,3aR)-3-((R)-1,5-Dimethyl-hexyl)-3a-methyl-7-phenylsulfanyl-2,3,3a,4,5,6-hexahydro-1H-indene → (+)-<2'R,6R,7R>-6-methyl-7-(6-methylhept-2-yl)-2-(phenylsulfonyl)bicyclo<4.3.0>-1-nonene (156137-92-7)

Guidance literature:

With peracetic acid; sodium acetate; In dichloromethane; water; acetic acid; for 16h; Yield given; Ambient temperature;

DOI:10.1080/00397919408011498

Reference yield:

Grundmann's ketone (66251-18-1) → (+)-<2'R,6R,7R>-6-methyl-7-(6-methylhept-2-yl)-2-(phenylsulfonyl)bicyclo<4.3.0>-1-nonene (156137-92-7)

Guidance literature:

Multi-step reaction with 2 steps

1: BF₃*H₂O / CH₂Cl₂ / 6 h / 0 °C

2: NaOAc, 33percent AcOOH in AcOH / CH₂Cl₂ / 16 h / 0 °C

With peracetic acid; boron trifluoride; sodium acetate; acetic acid; In dichloromethane;

DOI:10.1016/0040-4020(96)00147-0

upstream raw materials:

(+)-<2'R,6R,7R>-6-methyl-7-(6-methylhept-2-yl)-2-(phenylsulfonyl)bicyclo<4.3.0>-1,4-nonadiene

Grundmann's ketone

thiophenol

Downstream raw materials:

(+)-<1R,2'R,5R,6R,9R>-1-methyl-9-(6-methylhept-2-yl)-5-(phenylsulfonyl)bicyclo<4.3.0>nonane

(+)-<1R,2'R,5S,6R,9R>-1-methyl-9-(6-methylhept-2-yl)-5-(phenylsulfonyl)bicyclo<4.3.0>nonane