(2R,3S,4S,5R)-5-methoxy-7-((4-methoxybenzyl)oxy)-2,4-dimethylheptane-1,3-diol

Base Information

Chemical Name:(2R,3S,4S,5R)-5-methoxy-7-((4-methoxybenzyl)oxy)-2,4-dimethylheptane-1,3-diol
CAS No.:1551543-88-4
Molecular Formula:C₁₈H₃₀O₅
Molecular Weight:326.433
Hs Code.:

Synonyms:(2R,3S,4S,5R)-5-methoxy-7-((4-methoxybenzyl)oxy)-2,4-dimethylheptane-1,3-diol

Suppliers and Price of (2R,3S,4S,5R)-5-methoxy-7-((4-methoxybenzyl)oxy)-2,4-dimethylheptane-1,3-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (2R,3S,4S,5R)-5-methoxy-7-((4-methoxybenzyl)oxy)-2,4-dimethylheptane-1,3-diol

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of (2R,3S,4S,5R)-5-methoxy-7-((4-methoxybenzyl)oxy)-2,4-dimethylheptane-1,3-diol

There total 1 articles about (2R,3S,4S,5R)-5-methoxy-7-((4-methoxybenzyl)oxy)-2,4-dimethylheptane-1,3-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1551543-85-1
(2S,4R,5R)-1-((S)-4-benzyl-2-oxooxazolidin-3-yl)-5-methoxy-7-((4-methoxybenzyl)oxy)-2,4-dimethylheptane-1,3-dione

: 1551543-88-4
(2R,3S,4S,5R)-5-methoxy-7-((4-methoxybenzyl)oxy)-2,4-dimethylheptane-1,3-diol

: C₁₈H₃₀O₅

Guidance literature:: With lithium borohydride; In diethyl ether; at -26 - -15 ℃; for 0.333333h; Overall yield = 88 %; Overall yield = 0.207 g;
DOI:10.1021/ol500004k

Reference yield:

: 1551543-88-4
(2R,3S,4S,5R)-5-methoxy-7-((4-methoxybenzyl)oxy)-2,4-dimethylheptane-1,3-diol

: C₁₈H₂₈O₅

Guidance literature:: With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene; In dichloromethane; at 20 ℃; for 7h;
DOI:10.1021/ol500004k

Reference yield:

: 1551543-88-4
(2R,3S,4S,5R)-5-methoxy-7-((4-methoxybenzyl)oxy)-2,4-dimethylheptane-1,3-diol

: 1551543-91-9
(4R,5S,6R,7R,E)-5-((tert-butyldimethylsilyl)oxy)-7-methoxy-9-((4-methoxybenzyl)oxy)-2,4,6-trimethylnon-2-en-1-ol

Guidance literature:: Multi-step reaction with 4 steps

1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene / dichloromethane / 7 h / 20 °C

2: dichloromethane / 18 h / 20 °C

3: 2,6-dimethylpyridine / dichloromethane / 3 h / 0 °C

4: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 °C

With 2,6-dimethylpyridine; lithium aluminium tetrahydride; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene; In tetrahydrofuran; dichloromethane; 2: |Wittig Olefination;
DOI:10.1021/ol500004k