dimethyl (S_S,R)-(-)-2-oxo-4-(p-toluenesulfinylamino)-5,5-dimethylhexylphosphonate

Base Information

• Chemical Name: dimethyl (S_S,R)-(-)-2-oxo-4-(p-toluenesulfinylamino)-5,5-dimethylhexylphosphonate
• CAS No.: 814256-34-3
• Molecular Formula: C₁₇H₂₈NO₅PS
• Molecular Weight: 389.453

Synonyms:dimethyl (S_S,R)-(-)-2-oxo-4-(p-toluenesulfinylamino)-5,5-dimethylhexylphosphonate

Chemical Property of dimethyl (S_S,R)-(-)-2-oxo-4-(p-toluenesulfinylamino)-5,5-dimethylhexylphosphonate

Chemical Property:

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Technology Process of dimethyl (S_S,R)-(-)-2-oxo-4-(p-toluenesulfinylamino)-5,5-dimethylhexylphosphonate

There total 1 articles about dimethyl (S_S,R)-(-)-2-oxo-4-(p-toluenesulfinylamino)-5,5-dimethylhexylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

dimethyl methane phosphonate (756-79-6) + methyl (SS,R)-(+)-4,4-dimethyl-N-(p-toluenesulfinyl)-3-aminopentanoate (569352-10-9) → dimethyl (SS,R)-(-)-2-oxo-4-(p-toluenesulfinylamino)-5,5-dimethylhexylphosphonate (814256-34-3)

Guidance literature:

dimethyl methane phosphonate; With n-butyllithium; In tetrahydrofuran; cyclohexane; at -78 ℃; for 0.25h;

methyl (S_S,R)-(+)-4,4-dimethyl-N-(p-toluenesulfinyl)-3-aminopentanoate; In tetrahydrofuran; cyclohexane; at -78 ℃; for 2h;

DOI:10.1021/ol048157+

upstream raw materials:

dimethyl methane phosphonate

methyl (S_S,R)-(+)-4,4-dimethyl-N-(p-toluenesulfinyl)-3-aminopentanoate

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