Technology Process of C19H22BrNO2
There total 4 articles about C19H22BrNO2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C19H21BrN2;
With
water; hydrogen bromide; acetic acid;
at 20 - 145 ℃;
for 7h;
With
sodium hydrogencarbonate;
In
water;
pH=7;
Cooling with ice-water bath;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / -78 °C
1.2: 0.67 h / 20 °C
2.1: n-butyllithium; diisopropylamine / tetrahydrofuran; hexane / -78 °C
2.2: 0.5 h / -78 °C
3.1: water; hydrogen bromide; acetic acid / 7 h / 20 - 145 °C
3.2: pH 7 / Cooling with ice-water bath
With
n-butyllithium; water; hydrogen bromide; acetic acid; diisopropylamine;
In
tetrahydrofuran; hexane;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / -78 °C
1.2: 0.67 h / 20 °C
2.1: n-butyllithium; diisopropylamine / tetrahydrofuran; hexane / -78 °C
2.2: 0.5 h / -78 °C
3.1: water; hydrogen bromide; acetic acid / 7 h / 20 - 145 °C
3.2: pH 7 / Cooling with ice-water bath
With
n-butyllithium; water; hydrogen bromide; acetic acid; diisopropylamine;
In
tetrahydrofuran; hexane;