7-Cyano-4-hydroxy-3-quinolinecarboxylic acid

Base Information

Chemical Name:7-Cyano-4-hydroxy-3-quinolinecarboxylic acid
CAS No.:118078-26-5
Molecular Formula:C₁₁H₆N₂O₃
Molecular Weight:214.18
Hs Code.:
DSSTox Substance ID:DTXSID50467725
Wikidata:Q82294787
Mol file:118078-26-5.mol

Synonyms:118078-26-5;7-Cyano-4-hydroxy-3-quinolinecarboxylic acid;7-cyano-4-oxo-1H-quinoline-3-carboxylic Acid;3-Quinolinecarboxylic acid, 7-cyano-4-hydroxy-;7-CYANO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID;SCHEMBL2978491;SCHEMBL9691172;DTXSID50467725;AKOS015961399;AB25039;AC-13670;J-003700

Suppliers and Price of 7-Cyano-4-hydroxy-3-quinolinecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
7-CYANO-4-HYDROXY-3-QUINOLINECARBOXYLIC ACID 95.00%
5G
$ 1734.23

American Custom Chemicals Corporation
7-CYANO-4-HYDROXY-3-QUINOLINECARBOXYLIC ACID 95.00%
1G
$ 945.95

Total 3 raw suppliers

Chemical Property of 7-Cyano-4-hydroxy-3-quinolinecarboxylic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.686
Boiling Point:430.1°Cat760mmHg
Flash Point:213.9°C
PSA：93.95000
Density:1.54g/cm³
LogP:1.09798
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:214.03784206
Heavy Atom Count:16
Complexity:418

Purity/Quality:

98%Min ^*data from raw suppliers

7-CYANO-4-HYDROXY-3-QUINOLINECARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=C1C#N)NC=C(C2=O)C(=O)O

Technology Process of 7-Cyano-4-hydroxy-3-quinolinecarboxylic acid

There total 4 articles about 7-Cyano-4-hydroxy-3-quinolinecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 63463-18-3
ethyl 7-cyano-4-hydroxyquinoline-3-carboxylate

: 118078-26-5,874337-85-6
7-cyano-4-hydroxyquinoline-3-carboxylic acid

Guidance literature:: With sodium hydroxide; In water; for 0.5h; Reflux;
DOI:10.1016/j.bmc.2013.04.040

Reference yield:

: 2237-30-1
m-cyanoaniline

: 118078-26-5,874337-85-6
7-cyano-4-hydroxyquinoline-3-carboxylic acid

: 118078-25-4
5-cyano-4-hydroxy-quinoline-3-carboxylic acid

Guidance literature:

Reference yield:

: 2237-30-1
m-cyanoaniline

: 118078-26-5,874337-85-6
7-cyano-4-hydroxyquinoline-3-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 0.75 h / 110 °C

2: diphenylether / 1 h / Reflux

3: sodium hydroxide / water / 0.5 h / Reflux

With sodium hydroxide; In diphenylether; water;
DOI:10.1016/j.bmc.2013.04.040