N₄-acetyl-5'-O-(4,4'-dimethoxytriphenylmethyl)-5-phenylselenylmethyl-2'-deoxycytidine 3'-(2-cyanoethyl)-N,N-diisopropylphosphoramidite

Base Information

• Chemical Name: N₄-acetyl-5'-O-(4,4'-dimethoxytriphenylmethyl)-5-phenylselenylmethyl-2'-deoxycytidine 3'-(2-cyanoethyl)-N,N-diisopropylphosphoramidite
• CAS No.: 1043963-02-5
• Molecular Formula: C₄₈H₅₆N₅O₈PSe
• Molecular Weight: 940.935

Synonyms:N₄-acetyl-5'-O-(4,4'-dimethoxytriphenylmethyl)-5-phenylselenylmethyl-2'-deoxycytidine 3'-(2-cyanoethyl)-N,N-diisopropylphosphoramidite

Chemical Property of N₄-acetyl-5'-O-(4,4'-dimethoxytriphenylmethyl)-5-phenylselenylmethyl-2'-deoxycytidine 3'-(2-cyanoethyl)-N,N-diisopropylphosphoramidite

Chemical Property:

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Technology Process of N₄-acetyl-5'-O-(4,4'-dimethoxytriphenylmethyl)-5-phenylselenylmethyl-2'-deoxycytidine 3'-(2-cyanoethyl)-N,N-diisopropylphosphoramidite

There total 1 articles about N₄-acetyl-5'-O-(4,4'-dimethoxytriphenylmethyl)-5-phenylselenylmethyl-2'-deoxycytidine 3'-(2-cyanoethyl)-N,N-diisopropylphosphoramidite which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

2-cyanoethyl-N,N-diisopropylchlorophosphoramidite (100345-53-7) + N4-acetyl-5'-O-(4,4'-dimethoxytriphenylmethyl)-5-phenylselenylmethyl-2'-deoxycytidine (1043963-01-4) → N4-acetyl-5'-O-(4,4'-dimethoxytriphenylmethyl)-5-phenylselenylmethyl-2'-deoxycytidine 3'-(2-cyanoethyl)-N,N-diisopropylphosphoramidite (1043963-02-5)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 0.5h;

DOI:10.1021/ja802177u

upstream raw materials:

2-cyanoethyl-N,N-diisopropylchlorophosphoramidite

N₄-acetyl-5'-O-(4,4'-dimethoxytriphenylmethyl)-5-phenylselenylmethyl-2'-deoxycytidine

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