imidazole-1-carboxylic acid {(R)-1-[9-((1R,2S,3R,4S)-2,3-dihydroxy-4-propionylaminocyclopentyl)-6-(2,2-diphenylethylamino)-9H-purin-2-yl]pyrrolidin-3-yl}amide

Base Information

Chemical Name:imidazole-1-carboxylic acid {(R)-1-[9-((1R,2S,3R,4S)-2,3-dihydroxy-4-propionylaminocyclopentyl)-6-(2,2-diphenylethylamino)-9H-purin-2-yl]pyrrolidin-3-yl}amide
CAS No.:955972-57-3
Molecular Formula:C₃₅H₄₀N₁₀O₄
Molecular Weight:664.767
Hs Code.:

imidazole-1-carboxylic acid {(R)-1-[9-((1R,2S,3R,4S)-2,3-dihydroxy-4-propionylaminocyclopentyl)-6-(2,2-diphenylethylamino)-9H-purin-2-yl]pyrrolidin-3-yl}amide

Synonyms:imidazole-1-carboxylic acid {(R)-1-[9-((1R,2S,3R,4S)-2,3-dihydroxy-4-propionylaminocyclopentyl)-6-(2,2-diphenylethylamino)-9H-purin-2-yl]pyrrolidin-3-yl}amide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of imidazole-1-carboxylic acid {(R)-1-[9-((1R,2S,3R,4S)-2,3-dihydroxy-4-propionylaminocyclopentyl)-6-(2,2-diphenylethylamino)-9H-purin-2-yl]pyrrolidin-3-yl}amide

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Technology Process of imidazole-1-carboxylic acid {(R)-1-[9-((1R,2S,3R,4S)-2,3-dihydroxy-4-propionylaminocyclopentyl)-6-(2,2-diphenylethylamino)-9H-purin-2-yl]pyrrolidin-3-yl}amide

There total 1 articles about imidazole-1-carboxylic acid {(R)-1-[9-((1R,2S,3R,4S)-2,3-dihydroxy-4-propionylaminocyclopentyl)-6-(2,2-diphenylethylamino)-9H-purin-2-yl]pyrrolidin-3-yl}amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 884653-85-4
N-[(3aR,4S,6R,6aS)-6-[2-((R)-3-amino-pyrrolidin-1-yl)-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-2,2-dimethyl-tetrahydro-cyclopenta[1,3]dioxol-4-yl]-propionamide

: 530-62-1
1,1'-carbonyldiimidazole

: 955972-57-3
imidazole-1-carboxylic acid {(R)-1-[9-((1R,2S,3R,4S)-2,3-dihydroxy-4-propionylaminocyclopentyl)-6-(2,2-diphenylethylamino)-9H-purin-2-yl]pyrrolidin-3-yl}amide

Guidance literature:: In dichloromethane; at 20 ℃; for 3h;

Reference yield:

: 3731-51-9
2-(Aminomethyl)pyridine

: 955972-57-3
imidazole-1-carboxylic acid {(R)-1-[9-((1R,2S,3R,4S)-2,3-dihydroxy-4-propionylaminocyclopentyl)-6-(2,2-diphenylethylamino)-9H-purin-2-yl]pyrrolidin-3-yl}amide

: 76-05-1
trifluoroacetic acid

: 955967-54-1
N-((1S,2R,3S,4R)-4-{6-(2,2-diphenylethylamino)-2-[(R)-3-(3-pyridin-4-ylmethylureido)-pyrrolidin-1-yl]-purin-9-yl}-2,3-dihydroxycyclopentyl)propionamide trifluoroacetate

Guidance literature:: 2-(Aminomethyl)pyridine; imidazole-1-carboxylic acid {(R)-1-[9-((1R,2S,3R,4S)-2,3-dihydroxy-4-propionylaminocyclopentyl)-6-(2,2-diphenylethylamino)-9H-purin-2-yl]pyrrolidin-3-yl}amide; In dichloromethane; at 20 ℃;

trifluoroacetic acid; In water;

Reference yield:

: 955972-57-3
imidazole-1-carboxylic acid {(R)-1-[9-((1R,2S,3R,4S)-2,3-dihydroxy-4-propionylaminocyclopentyl)-6-(2,2-diphenylethylamino)-9H-purin-2-yl]pyrrolidin-3-yl}amide

: 591-27-5
m-Hydroxyaniline

: 76-05-1
trifluoroacetic acid

: 955967-92-7
N-[(1S,2R,3S,4R)-4-(6-(2,2-diphenylethylamino)-2-{(R)-3-[3-(3-hydroxyphenyl)ureido]pyrrolidin-1-yl}purin-9-yl)-2,3-dihydroxycyclopentyl]propionamide trifluoroacetate

Guidance literature:: imidazole-1-carboxylic acid {(R)-1-[9-((1R,2S,3R,4S)-2,3-dihydroxy-4-propionylaminocyclopentyl)-6-(2,2-diphenylethylamino)-9H-purin-2-yl]pyrrolidin-3-yl}amide; m-Hydroxyaniline; In dichloromethane; at 20 ℃;

trifluoroacetic acid; In water; at 20 ℃; for 3h;