(1-((1-benzyl-1H-indol-3-yl)(hydroxy)methyl)cyclopropyl)(phenyl)-methanone

Base Information

Chemical Name:(1-((1-benzyl-1H-indol-3-yl)(hydroxy)methyl)cyclopropyl)(phenyl)-methanone
CAS No.:1226783-79-4
Molecular Formula:C₂₆H₂₃NO₂
Molecular Weight:381.474
Hs Code.:

Synonyms:(1-((1-benzyl-1H-indol-3-yl)(hydroxy)methyl)cyclopropyl)(phenyl)-methanone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1-((1-benzyl-1H-indol-3-yl)(hydroxy)methyl)cyclopropyl)(phenyl)-methanone

Chemical Property:

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Technology Process of (1-((1-benzyl-1H-indol-3-yl)(hydroxy)methyl)cyclopropyl)(phenyl)-methanone

There total 1 articles about (1-((1-benzyl-1H-indol-3-yl)(hydroxy)methyl)cyclopropyl)(phenyl)-methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 3481-02-5
cyclopropyl phenyl ketone

: 10511-51-0
1-Benzylindole-3-carboxaldehyde

: 1226783-79-4
(1-((1-benzyl-1H-indol-3-yl)(hydroxy)methyl)cyclopropyl)(phenyl)-methanone

Guidance literature:: cyclopropyl phenyl ketone; With 2,2,6,6-tetramethyl-piperidine; n-butyllithium; In tetrahydrofuran; hexane; at 0 ℃;

1-Benzylindole-3-carboxaldehyde; In tetrahydrofuran; hexane; at 0 - 20 ℃;
DOI:10.1021/jo1005125

Reference yield: 95.0%

: 1226783-79-4
(1-((1-benzyl-1H-indol-3-yl)(hydroxy)methyl)cyclopropyl)(phenyl)-methanone

: 693-02-7
hex-1-yne

: 1226783-70-5
1-(1-((1-benzyl-1H-indol-3-yl)(hydroxy)methyl)cyclopropyl)-1-phenylhept-2-yn-1-ol

Guidance literature:: hex-1-yne; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃;

(1-((1-benzyl-1H-indol-3-yl)(hydroxy)methyl)cyclopropyl)(phenyl)-methanone; In tetrahydrofuran; hexane; at -78 - 20 ℃;

With ammonium chloride; In tetrahydrofuran; hexane; water; optical yield given as %de;
DOI:10.1021/jo1005125

Reference yield:

: 1226783-79-4
(1-((1-benzyl-1H-indol-3-yl)(hydroxy)methyl)cyclopropyl)(phenyl)-methanone

: 65032-27-1
ethynylmagnesium chloride

: 1226783-80-7
1-(1-((1-benzyl-1H-indol-3-yl)(hydroxy)methyl)cyclopropyl)-1-phenylprop-2-yn-1-ol

Guidance literature:: (1-((1-benzyl-1H-indol-3-yl)(hydroxy)methyl)cyclopropyl)(phenyl)-methanone; ethynylmagnesium chloride; In tetrahydrofuran; toluene; at -78 - 20 ℃;

With ammonium chloride; In tetrahydrofuran; water; toluene;
DOI:10.1021/jo1005125