biphenyl-2-yl-carbamic acid 1-[2-(benzylmethylamino)ethyl]piperidin-4-yl ester

Base Information

• Chemical Name: biphenyl-2-yl-carbamic acid 1-[2-(benzylmethylamino)ethyl]piperidin-4-yl ester
• CAS No.: 864686-28-2
• Molecular Formula: C₂₈H₃₃N₃O₂
• Molecular Weight: 443.589
• Mol file: 864686-28-2.mol

Synonyms:biphenyl-2-yl-carbamic acid 1-[2-(benzylmethylamino)ethyl]piperidin-4-yl ester

Chemical Property of biphenyl-2-yl-carbamic acid 1-[2-(benzylmethylamino)ethyl]piperidin-4-yl ester

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of biphenyl-2-yl-carbamic acid 1-[2-(benzylmethylamino)ethyl]piperidin-4-yl ester

There total 3 articles about biphenyl-2-yl-carbamic acid 1-[2-(benzylmethylamino)ethyl]piperidin-4-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

N-Benzyl-N-methylaminoacetaldehyde + 4-piperidyl N-(2-biphenyl)carbamate (171722-92-2) → biphenyl-2-yl-carbamic acid 1-[2-(benzylmethylamino)ethyl]piperidin-4-yl ester (864686-28-2)

Guidance literature:

With sodium tris(acetoxy)borohydride; In 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran; isopropyl alcohol;

Reference yield:

C11H17NO3S (379267-43-3) + 4-piperidyl N-(2-biphenyl)carbamate (171722-92-2) → biphenyl-2-yl-carbamic acid 1-[2-(benzylmethylamino)ethyl]piperidin-4-yl ester (864686-28-2)

Guidance literature:

C₁₁H₁₇NO₃S; 4-piperidyl N-(2-biphenyl)carbamate; In dichloromethane; at 5 - 20 ℃; for 3.5h;

With sodium hydroxide; In dichloromethane; water; Product distribution / selectivity;

Reference yield:

2-(N-benzyl-N-methyl)amino-1-ethanol (101-98-4) + 4-piperidyl N-(2-biphenyl)carbamate (171722-92-2) → biphenyl-2-yl-carbamic acid 1-[2-(benzylmethylamino)ethyl]piperidin-4-yl ester (864686-28-2)

Guidance literature:

2-(N-benzyl-N-methyl)amino-1-ethanol; With sodium hydroxide; tetrabutyl-ammonium chloride; methanesulfonyl chloride; In dichloromethane; water; at -10 ℃; for 0.916667h;

4-piperidyl N-(2-biphenyl)carbamate; In dichloromethane; water; at 5 - 10 ℃; for 3.5h; Product distribution / selectivity;

upstream raw materials:

4-piperidyl N-(2-biphenyl)carbamate

C₁₁H₁₇NO₃S

2-(N-benzyl-N-methyl)amino-1-ethanol

Downstream raw materials:

biphenyl-2-ylcarbamic acid 1-[2-(methylamino)ethyl]piperidin-4-yl ester