4,5-bis(ethoxycarbonylmethoxy)-2-nitrobenzyl alcohol methanesulfonate

Base Information

Chemical Name:4,5-bis(ethoxycarbonylmethoxy)-2-nitrobenzyl alcohol methanesulfonate
CAS No.:939438-95-6
Molecular Formula:C₁₆H₂₁NO₁₁S
Molecular Weight:435.409
Hs Code.:

Synonyms:4,5-bis(ethoxycarbonylmethoxy)-2-nitrobenzyl alcohol methanesulfonate

Suppliers and Price of 4,5-bis(ethoxycarbonylmethoxy)-2-nitrobenzyl alcohol methanesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4,5-bis(ethoxycarbonylmethoxy)-2-nitrobenzyl alcohol methanesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4,5-bis(ethoxycarbonylmethoxy)-2-nitrobenzyl alcohol methanesulfonate

There total 3 articles about 4,5-bis(ethoxycarbonylmethoxy)-2-nitrobenzyl alcohol methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 160888-74-4
4,5-bis-(ethoxycarbonylmethoxy)-2-nitrobenzaldehyde

: 939438-95-6
4,5-bis(ethoxycarbonylmethoxy)-2-nitrobenzyl alcohol methanesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: 67 percent / NaBH₄; AcOH / CH₂Cl₂; ethanol / 1.5 h / 0 - 5 °C

2: 90 percent / Et₃N / CH₂Cl₂ / 3.5 h / 0 - 20 °C

With sodium tetrahydroborate; acetic acid; triethylamine; In ethanol; dichloromethane;
DOI:10.1021/ja069361q

Reference yield:

: 119309-58-9
(2-ethoxycarbonylmethoxy-5-formyl-phenoxy)-acetic acid ethyl ester

: 939438-95-6
4,5-bis(ethoxycarbonylmethoxy)-2-nitrobenzyl alcohol methanesulfonate

Guidance literature:: Multi-step reaction with 3 steps

1: 86 percent / KNO₃; TFA / 16 h / 0 - 20 °C

2: 67 percent / NaBH₄; AcOH / CH₂Cl₂; ethanol / 1.5 h / 0 - 5 °C

3: 90 percent / Et₃N / CH₂Cl₂ / 3.5 h / 0 - 20 °C

With sodium tetrahydroborate; acetic acid; potassium nitrate; triethylamine; trifluoroacetic acid; In ethanol; dichloromethane;
DOI:10.1021/ja069361q

Reference yield:

: 139-85-5
3,4-dihydroxybenzaldehyde

: 939438-95-6
4,5-bis(ethoxycarbonylmethoxy)-2-nitrobenzyl alcohol methanesulfonate

Guidance literature:: Multi-step reaction with 4 steps

1.1: K₂CO₃ / dimethylformamide / 0.5 h

1.2: 89 percent / dimethylformamide / 16.5 h / 0 - 20 °C

2.1: 86 percent / KNO₃; TFA / 16 h / 0 - 20 °C

3.1: 67 percent / NaBH₄; AcOH / CH₂Cl₂; ethanol / 1.5 h / 0 - 5 °C

4.1: 90 percent / Et₃N / CH₂Cl₂ / 3.5 h / 0 - 20 °C

With sodium tetrahydroborate; potassium carbonate; acetic acid; potassium nitrate; triethylamine; trifluoroacetic acid; In ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja069361q