N-benzyl-N-methyl-4-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)but-3-en-1-amine

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Chemical Name:N-benzyl-N-methyl-4-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)but-3-en-1-amine
CAS No.:1254705-09-3
Molecular Formula:C₃₀H₃₆N₂O
Molecular Weight:440.629
Hs Code.:

Synonyms:N-benzyl-N-methyl-4-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)but-3-en-1-amine

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Chemical Property of N-benzyl-N-methyl-4-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)but-3-en-1-amine

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Technology Process of N-benzyl-N-methyl-4-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)but-3-en-1-amine

There total 1 articles about N-benzyl-N-methyl-4-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)but-3-en-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1254705-08-2
(3-(benzyl(methyl)amino)propyl)triphenylphosphonium bromide

: 179018-53-2
phenyl(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)methanone

: 1254705-09-3
N-benzyl-N-methyl-4-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)but-3-en-1-amine

Guidance literature:: (3-(benzyl(methyl)amino)propyl)triphenylphosphonium bromide; With n-butyllithium; In tetrahydrofuran; at 0 ℃; for 0.833333h; Inert atmosphere;

phenyl(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)methanone; In tetrahydrofuran; at 0 - 20 ℃; Further stages; Inert atmosphere;
DOI:10.1021/jm100666w

Reference yield: 88.0%

: 1254705-09-3
N-benzyl-N-methyl-4-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)but-3-en-1-amine

: 1254704-90-9
N-methyl-4-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)butan-1-amine

Guidance literature:: With 20% palladium hydroxide on carbon; hydrogen; In methanol; at 20 ℃; for 48h; under 1551.49 Torr;
DOI:10.1021/jm100666w