Dipropan-2-yl 2,2-dioxo-1,3,2-dioxathiolane-4,5-dicarboxylate

Base Information

• Chemical Name: Dipropan-2-yl 2,2-dioxo-1,3,2-dioxathiolane-4,5-dicarboxylate
• CAS No.: 117470-88-9
• Molecular Formula: C₁₀H₁₆O₈S
• Molecular Weight: 296.298
• DSSTox Substance ID: DTXSID80401637
• Mol file: 117470-88-9.mol

Synonyms:Dipropan-2-yl 2,2-dioxo-1,3,2-dioxathiolane-4,5-dicarboxylate;117470-88-9;DIISOPROPYL (4R,5R)-1,3,2-DIOXATHIOLANE- 4,5-DICA.LA.DIOXIDE;SCHEMBL20253776;DTXSID80401637

Chemical Property of Dipropan-2-yl 2,2-dioxo-1,3,2-dioxathiolane-4,5-dicarboxylate

Chemical Property:

• Refractive Index: n20/D 1.434
• Flash Point: 110 °C
• PSA: 113.58000
• LogP: 0.99920
• Storage Temp.: 2-8°C
• XLogP3: 1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 6
• Exact Mass: 296.05658864
• Heavy Atom Count: 19
• Complexity: 411

Purity/Quality:

Safty Information:

• Safety Statements: 23-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)OC(=O)C1C(OS(=O)(=O)O1)C(=O)OC(C)C

Technology Process of Dipropan-2-yl 2,2-dioxo-1,3,2-dioxathiolane-4,5-dicarboxylate

There total 4 articles about Dipropan-2-yl 2,2-dioxo-1,3,2-dioxathiolane-4,5-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

D-(-)-diisopropyl tartrate (62961-64-2) → (4S,5S)-2,2-Dioxo-2λ6-[1,3,2]dioxathiolane-4,5-dicarboxylic acid diisopropyl ester (127854-45-9,117470-88-9)

Guidance literature:

With ruthenium trichloride; sodium periodate; thionyl chloride; Yield given. Multistep reaction; 1.) CCl₄, reflux, 30 min, 2.) CH₃CN/H₂O, room temperature, 60 min;

DOI:10.1021/ja00230a045

Reference yield:

(4S,5S)-2-Oxo-2λ4-[1,3,2]dioxathiolane-4,5-dicarboxylic acid diisopropyl ester → (4S,5S)-2,2-Dioxo-2λ6-[1,3,2]dioxathiolane-4,5-dicarboxylic acid diisopropyl ester (127854-45-9,117470-88-9)

Guidance literature:

With ruthenium trichloride; sodium periodate; In water; acetonitrile;

DOI:10.1016/S0040-4039(98)00190-7

Reference yield:

(4R,5R)-2-Oxo-2λ4-[1,3,2]dioxathiolane-4,5-dicarboxylic acid diisopropyl ester (136029-38-4) → (-)-diisopropyltartrate-2,3-cyclic sulfate (117470-88-9)

Guidance literature:

With ruthenium trichloride; sodium periodate; In water; acetonitrile;

DOI:10.1016/S0040-4039(98)00190-7

upstream raw materials:

D-(-)-diisopropyl tartrate

(4R,5R)-2-Oxo-2λ⁴-[1,3,2]dioxathiolane-4,5-dicarboxylic acid diisopropyl ester

L-(+)-diisopropyl tartrate