Ethanethiol, 2-[(2-methylcyclopentyl)oxy]-, trans- (9CI)

Base Information

• Chemical Name: Ethanethiol, 2-[(2-methylcyclopentyl)oxy]-, trans- (9CI)
• CAS No.: 117391-09-0
• Molecular Formula: C8H16 O S
• Molecular Weight: 160.28
• Mol file: 117391-09-0.mol

Synonyms:Ethanethiol, 2-[(2-methylcyclopentyl)oxy]-, trans- (9CI)

Chemical Property of Ethanethiol, 2-[(2-methylcyclopentyl)oxy]-, trans- (9CI)

Chemical Property:

• PSA: 48.03000
• LogP: 2.12140

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethanethiol, 2-[(2-methylcyclopentyl)oxy]-, trans- (9CI)

There total 3 articles about Ethanethiol, 2-[(2-methylcyclopentyl)oxy]-, trans- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

2-(4-pentenyl)-1,3-oxathiolane (117391-06-7) → 1-methyl-2-(1-oxa-4-mercaptobutyl)cyclopentane (117391-09-0) + 2-((1R,2S)-2-Methyl-cyclopentylsulfanyl)-ethanethiol (117391-07-8,117391-08-9)

Guidance literature:

With tri-n-butyl-tin hydride; 2,2'-azobis(isobutyronitrile); In benzene; at 80 ℃; for 24h; Yields of byproduct given;

DOI:10.1016/S0040-4039(00)82476-4

Reference yield: 60.0%

2-(4-pentenyl)-1,3-oxathiolane (117391-06-7) → 1-methyl-2-(1-oxa-4-mercaptobutyl)cyclopentane (117391-09-0)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; for 30h; Heating;

Reference yield:

hex-5-en-1-al (764-59-0) → 1-methyl-2-(1-oxa-4-mercaptobutyl)cyclopentane (117391-09-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / Na₂SO₄, ZnCl₂ / dioxane / a) 0 deg C, 10 min, b) 22 deg C, 20 h

2: 60 percent / n-Bu₃SnH, AIBN / benzene / 30 h / Heating

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; sodium sulfate; zinc(II) chloride; In 1,4-dioxane; benzene;

upstream raw materials:

2-(4-pentenyl)-1,3-oxathiolane

hex-5-en-1-al

Downstream raw materials:

trans-2-methylcyclopentanol

Refernces

• 1、 Yadav, Veejendra K.,Fallis, Alex G.. "CYCLOPENTANE SYNTHESIS and ANNULATION: INTRAMOLECULAR RADICAL CYCLIZATION of ACETALS". . p. 897 - 900. Retrieved 2007/10/02.