Thieno[3,2-b]pyridin-6-ylmethanol

Base Information

• Chemical Name: Thieno[3,2-b]pyridin-6-ylmethanol
• CAS No.: 117390-33-7
• Molecular Formula: C₈H₇NOS
• Molecular Weight: 165.216
• DSSTox Substance ID: DTXSID00554538
• Wikidata: Q82435586
• Mol file: 117390-33-7.mol

Synonyms:thieno[3,2-b]pyridin-6-ylmethanol;117390-33-7;Thieno[3,2-b]pyridine-6-methanol (9CI);SCHEMBL6605559;DTXSID00554538;(Thieno[3,2-b]pyridin-6-yl)methanol

Chemical Property of Thieno[3,2-b]pyridin-6-ylmethanol

Chemical Property:

• PSA: 61.36000
• LogP: 1.78860
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 165.02483502
• Heavy Atom Count: 11
• Complexity: 142

Purity/Quality:

98%min ^*data from raw suppliers

Thieno[3,2-b]pyridine-6-methanol 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CSC2=C1N=CC(=C2)CO

Technology Process of Thieno[3,2-b]pyridin-6-ylmethanol

There total 1 articles about Thieno[3,2-b]pyridin-6-ylmethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.0%

5-chloro-6-formyl thieno<3,2-b>pyridine (65977-56-2) → 6-hydroxymethyl thieno<3,2-b>pyridine (117390-33-7) + 6-hydroxymethyl 5-chloro thieno<3,2-b>pyridine (117390-34-8)

Guidance literature:

With acetic acid; zinc; In water; at 75 ℃; for 4h;

DOI:10.1016/S0040-4020(01)85888-9

upstream raw materials:

5-chloro-6-formyl thieno<3,2-b>pyridine