isoquinoline N-p-benzenesulphonylimine

Base Information

• Chemical Name: isoquinoline N-p-benzenesulphonylimine
• CAS No.: 75586-27-5
• Molecular Formula: C₁₅H₁₂N₂O₂S
• Molecular Weight: 284.338
• Mol file: 75586-27-5.mol

Synonyms:isoquinoline N-p-benzenesulphonylimine

Chemical Property of isoquinoline N-p-benzenesulphonylimine

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of isoquinoline N-p-benzenesulphonylimine

There total 5 articles about isoquinoline N-p-benzenesulphonylimine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

C15H12N2O2S → isoquinoline N-p-benzenesulphonylimine (75586-27-5)

Guidance literature:

With sodium carbonate; In ethanol; water; for 24h; Ambient temperature; dark;

Reference yield: 37.0%

2-(2-oxoethyl)benzaldehyde (25705-34-4) + benzenesufonyl hydrazide (80-17-1) → isoquinoline N-p-benzenesulphonylimine (75586-27-5)

Guidance literature:

hydrogenchloride; In ethanol; for 48h; Ambient temperature;

DOI:10.1055/s-1985-31128

Reference yield: 23.0%

isoquinoline (119-65-3) + p-toluenesulfonyl chloride (98-59-9) → isoquinoline N-p-benzenesulphonylimine (75586-27-5)

Guidance literature:

isoquinoline; With O-(2,4-dinitrophenyl)hydroxylamine; In tetrahydrofuran; water; at 40 ℃; for 12h;

p-toluenesulfonyl chloride; In tetrahydrofuran; for 0.5h;

p-toluenesulfonyl chloride; With sodium hydroxide; In tetrahydrofuran; water; at 20 ℃;

DOI:10.1021/jo200863e

upstream raw materials:

2-(2-oxoethyl)benzaldehyde

benzenesufonyl hydrazide

2-ethynylbenzaldehyde

isoquinoline