N-{9-[4'-(3-pyrrolidin-1-yl-propionylamino)-phenylamino]}-3,6-bis(3-pyrrolidinopropionamido)acridine

Base Information

Chemical Name:N-{9-[4'-(3-pyrrolidin-1-yl-propionylamino)-phenylamino]}-3,6-bis(3-pyrrolidinopropionamido)acridine
CAS No.:393570-34-8
Molecular Formula:C₄₀H₅₀N₈O₃
Molecular Weight:690.889
Hs Code.:

Synonyms:N-{9-[4'-(3-pyrrolidin-1-yl-propionylamino)-phenylamino]}-3,6-bis(3-pyrrolidinopropionamido)acridine

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Chemical Property of N-{9-[4'-(3-pyrrolidin-1-yl-propionylamino)-phenylamino]}-3,6-bis(3-pyrrolidinopropionamido)acridine

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Technology Process of N-{9-[4'-(3-pyrrolidin-1-yl-propionylamino)-phenylamino]}-3,6-bis(3-pyrrolidinopropionamido)acridine

There total 5 articles about N-{9-[4'-(3-pyrrolidin-1-yl-propionylamino)-phenylamino]}-3,6-bis(3-pyrrolidinopropionamido)acridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 393570-34-8
N-{9-[4'-(3-pyrrolidin-1-yl-propionylamino)-phenylamino]}-3,6-bis(3-pyrrolidinopropionamido)acridine

Guidance literature:

Reference yield: 60.0%

: 393570-64-4
N-(4-amino-phenyl)-3-(pyrrolidin-1-yl)-propionamide

: 351351-79-6
N-[9-chloro-6-(3-pyrrolidin-1-yl-propionylamino)-acridin-3-yl]-3-pyrrolidin-1-yl-propionoamide

: 393570-34-8
N-{9-[4'-(3-pyrrolidin-1-yl-propionylamino)-phenylamino]}-3,6-bis(3-pyrrolidinopropionamido)acridine

Guidance literature:: In methanol; for 15h; Heating;
DOI:10.1021/jm050555a

Reference yield:

: 851651-95-1
N-(4-nitro-phenyl)-3-(pyrrolidin-1-yl)-propionamide

: 393570-34-8
N-{9-[4'-(3-pyrrolidin-1-yl-propionylamino)-phenylamino]}-3,6-bis(3-pyrrolidinopropionamido)acridine

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / ammonium formate / Pd/C

2: 60 percent / methanol / 15 h / Heating

With ammonium formate; palladium on activated charcoal; In methanol;
DOI:10.1021/jm050555a