C₂₅H₁₂BrN

Base Information

• Chemical Name: C₂₅H₁₂BrN
• CAS No.: 1332831-26-1
• Molecular Formula: C₂₅H₁₂BrN
• Molecular Weight: 406.281
• Mol file: 1332831-26-1.mol

Synonyms:C₂₅H₁₂BrN

Chemical Property of C₂₅H₁₂BrN

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₁₂BrN

There total 1 articles about C₂₅H₁₂BrN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

1,6-dibromopyrene (27973-29-1) + 4-cyanophenylacetylene (3032-92-6) → C25H12BrN (1332831-26-1)

Guidance literature:

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In N,N-dimethyl-formamide; at 80 ℃;

DOI:10.1016/j.tetlet.2011.06.089

Reference yield: 66.0%

C25H12BrN (1332831-26-1) + trimethylsilylacetylene (1066-54-2) → C27H13N (1332831-27-2)

Guidance literature:

C₂₅H₁₂BrN; trimethylsilylacetylene; With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; In toluene; at 90 ℃;

With potassium carbonate; In tetrahydrofuran; methanol; at 20 ℃; for 2h;

DOI:10.1016/j.tetlet.2011.06.089

Reference yield:

C25H12BrN (1332831-26-1) → C38H25N5O4 (1332831-25-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine / toluene / 90 °C

1.2: 2 h / 20 °C

2.1: copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine / N,N-dimethyl-formamide / 2 h / 80 °C

3.1: ammonium hydroxide / methanol / 60 °C

With ammonium hydroxide; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; In methanol; N,N-dimethyl-formamide; toluene; 1.1: Sonogashira cross-coupling / 2.1: Sonogashira cross-coupling;

DOI:10.1016/j.tetlet.2011.06.089

upstream raw materials:

1,6-dibromopyrene

4-cyanophenylacetylene

Downstream raw materials:

C₃₈H₂₅N₅O₃

C₃₈H₂₅N₅O₄

C₄₁H₃₀N₆O₃

C₂₇H₁₃N