Cyclobutanecarboxylic acid, 1-amino-3-(hydroxymethyl)-, trans- (9CI)

Base Information

Chemical Name:Cyclobutanecarboxylic acid, 1-amino-3-(hydroxymethyl)-, trans- (9CI)
CAS No.:116823-32-6
Molecular Formula:C₆H₁₁NO₃
Molecular Weight:145.158
Hs Code.:
Mol file:116823-32-6.mol

Synonyms:Cyclobutanecarboxylic acid, 1-amino-3-(hydroxymethyl)-, trans- (9CI)

Suppliers and Price of Cyclobutanecarboxylic acid, 1-amino-3-(hydroxymethyl)-, trans- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of Cyclobutanecarboxylic acid, 1-amino-3-(hydroxymethyl)-, trans- (9CI)

Chemical Property:

Boiling Point:326.2±17.0 °C(Predicted)
PKA:2.26±0.40(Predicted)
PSA：83.55000
Density:1.346±0.06 g/cm3(Predicted)
LogP:-0.12890

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Cyclobutanecarboxylic acid, 1-amino-3-(hydroxymethyl)-, trans- (9CI)

There total 3 articles about Cyclobutanecarboxylic acid, 1-amino-3-(hydroxymethyl)-, trans- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 161181-57-3
trans-1-(benzoylamino)-3-(hydroxymethyl)cyclobutane-1-N,N-pentamethylenecarboxamide

: 116823-32-6,1555492-59-5
trans-1-amino-3-(hydroxymethyl)cyclobutane-1-carboxylic acid

Guidance literature:: With hydrogenchloride; at 130 ℃; for 20h;
DOI:10.1021/jm960390t

Reference yield: 66.0%

: 116823-33-7
3-oxabicyclo<3.1.1>heptan-2-onyl-1-isocyanate

: 116823-32-6,1555492-59-5
trans-1-amino-3-(hydroxymethyl)cyclobutane-1-carboxylic acid

Guidance literature:: With hydrogenchloride; at 100 ℃; for 4h;
DOI:10.1016/S0040-4020(01)90351-5

Reference yield:

: 17160-65-5
3-oxabicyclo<3.1.1>heptan-2-one-1-carboxylic acid

: 116823-32-6,1555492-59-5
trans-1-amino-3-(hydroxymethyl)cyclobutane-1-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / sodium azide / acetone / 4 h / 0 °C

2: 66 percent / aq. HCl / 4 h / 100 °C

With hydrogenchloride; sodium azide; In acetone;
DOI:10.1016/S0040-4020(01)90351-5