(2R)-2-(2-phenylethyl)pyrrolidine

Base Information

Chemical Name:(2R)-2-(2-phenylethyl)pyrrolidine
CAS No.:130343-16-7
Molecular Formula:C₁₂H₁₇N
Molecular Weight:175.274
Hs Code.:
DSSTox Substance ID:DTXSID401300182

Synonyms:(2R)-2-(2-phenylethyl)pyrrolidine;SCHEMBL6535590;DTXSID401300182;130343-16-7

Suppliers and Price of (2R)-2-(2-phenylethyl)pyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R)-2-(2-phenylethyl)pyrrolidine

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:175.136099547
Heavy Atom Count:13
Complexity:138

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC(NC1)CCC2=CC=CC=C2
Isomeric SMILES:C1C[C@H](NC1)CCC2=CC=CC=C2

Technology Process of (2R)-2-(2-phenylethyl)pyrrolidine

There total 6 articles about (2R)-2-(2-phenylethyl)pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 283610-06-0
(2R)-2-phenyl-2-[(2'R)-2'-phenylethyl-N-pyrrolidinyl]-1-ethanol

: 130343-16-7
(+)-2-phenylethylpyrrolidine

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethyl acetate; at 20 ℃; under 6840.46 Torr;
DOI:10.1002/(SICI)1099-0690(200005)2000:9<1719::AID-EJOC1719>3.0.CO;2-R

Reference yield:

: (S)-N-triflyl-2-[(E)-2-phenylethenyl]pyrrolidine

: 130343-16-7
(+)-2-phenylethylpyrrolidine

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; for 24h; Heating;
DOI:10.1021/ja039774g

Reference yield:

: (3R)-3-phenyl-7a-(phenylethyl)perhydropyrrolo[2,1-b][1,3]oxazole

: 130343-16-7
(+)-2-phenylethylpyrrolidine

Guidance literature:: Multi-step reaction with 2 steps

1: LiBHEt₃ / tetrahydrofuran / 10 h / 0 °C

2: H₂ / Pd/C / ethyl acetate / 20 °C / 6840.46 Torr

With hydrogen; lithium triethylborohydride; palladium on activated charcoal; In tetrahydrofuran; ethyl acetate; 1: Reduction / 2: Hydrogenolysis;
DOI:10.1002/(SICI)1099-0690(200005)2000:9<1719::AID-EJOC1719>3.0.CO;2-R