5,17-Bis<<3-formyl-2-(2-propenyloxy)phenoxy>acetamido>-25,26,27,28-tetrapropoxycalix<4>arene

Base Information

• Chemical Name: 5,17-Bis<<3-formyl-2-(2-propenyloxy)phenoxy>acetamido>-25,26,27,28-tetrapropoxycalix<4>arene
• CAS No.: 156874-52-1
• Molecular Formula: C₆₄H₇₀N₂O₁₂
• Molecular Weight: 1059.27
• Mol file: 156874-52-1.mol

Synonyms:5,17-Bis<<3-formyl-2-(2-propenyloxy)phenoxy>acetamido>-25,26,27,28-tetrapropoxycalix<4>arene

Chemical Property of 5,17-Bis<<3-formyl-2-(2-propenyloxy)phenoxy>acetamido>-25,26,27,28-tetrapropoxycalix<4>arene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,17-Bis<<3-formyl-2-(2-propenyloxy)phenoxy>acetamido>-25,26,27,28-tetrapropoxycalix<4>arene

There total 2 articles about 5,17-Bis<<3-formyl-2-(2-propenyloxy)phenoxy>acetamido>-25,26,27,28-tetrapropoxycalix<4>arene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

2-allyloxy-3-hydroxybenzaldehyde (108059-04-7) + 5,17-Bis(2-chloroacetamido)-25,26,27,28-tetrapropoxycalix<4>arene (156874-50-9,168753-17-1) → 5,17-Bis<<3-formyl-2-(2-propenyloxy)phenoxy>acetamido>-25,26,27,28-tetrapropoxycalix<4>arene (156874-52-1)

Guidance literature:

With potassium carbonate; potassium iodide; In acetonitrile; for 12h; Heating;

DOI:10.1021/jo00092a031

Reference yield:

5,17-diamino-25,26,27,28-tetrakis(propyloxy)calix[4]arene (156874-49-6,169436-70-8,950744-70-4,1078151-72-0) → 5,17-Bis<<3-formyl-2-(2-propenyloxy)phenoxy>acetamido>-25,26,27,28-tetrapropoxycalix<4>arene (156874-52-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 69 percent / Et₃N / CH₂Cl₂ / 1 h

2: 59 percent / K₂CO₃, KI / acetonitrile / 12 h / Heating

With potassium carbonate; triethylamine; potassium iodide; In dichloromethane; acetonitrile;

DOI:10.1021/jo00092a031

Reference yield: 79.0%

5,17-Bis<<3-formyl-2-(2-propenyloxy)phenoxy>acetamido>-25,26,27,28-tetrapropoxycalix<4>arene (156874-52-1) → 5,17-Bis<(3-formyl-2-hydroxyphenoxy)acetamido>-25,26,27,28-tetrapropoxycalix<4>arene

Guidance literature:

With palladium diacetate; formic acid; triethylamine; triphenylphosphine; In ethanol; for 1h; Heating;

DOI:10.1021/jo00092a031

upstream raw materials:

2-allyloxy-3-hydroxybenzaldehyde

5,17-Bis(2-chloroacetamido)-25,26,27,28-tetrapropoxycalix<4>arene

5,17-diamino-25,26,27,28-tetrakis(propyloxy)calix[4]arene