Pyrrolo[1,2-a]pyrazine-1,4-dione, 3-ethylidenehexahydro-, (3Z,8aS)- (9CI)

Base Information

Chemical Name:Pyrrolo[1,2-a]pyrazine-1,4-dione, 3-ethylidenehexahydro-, (3Z,8aS)- (9CI)
CAS No.:114604-89-6
Molecular Formula:C₉H₁₂N₂O₂
Molecular Weight:180.206
Hs Code.:
Mol file:114604-89-6.mol

Synonyms:Pyrrolo[1,2-a]pyrazine-1,4-dione,3-ethylidenehexahydro-, [S-(Z)]-

Suppliers and Price of Pyrrolo[1,2-a]pyrazine-1,4-dione, 3-ethylidenehexahydro-, (3Z,8aS)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of Pyrrolo[1,2-a]pyrazine-1,4-dione, 3-ethylidenehexahydro-, (3Z,8aS)- (9CI)

Chemical Property:

PSA：52.90000
LogP:0.22480

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Pyrrolo[1,2-a]pyrazine-1,4-dione, 3-ethylidenehexahydro-, (3Z,8aS)- (9CI)

There total 3 articles about Pyrrolo[1,2-a]pyrazine-1,4-dione, 3-ethylidenehexahydro-, (3Z,8aS)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7
L-proline

: 114604-89-6,160706-82-1
(S)-3-Eth-(Z)-ylidene-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione

Guidance literature:: Multi-step reaction with 2 steps

1: NaHCO₃ / 2-methyl-propan-2-ol

With sodium hydrogencarbonate; In tert-butyl alcohol;
DOI:10.1016/S0040-4039(98)01599-8

Reference yield:

: 15761-39-4,59433-50-0
1-(tert-butoxycarbonyl)-L-proline

: 600-18-0
2-Oxobutyric acid

: 114604-89-6,160706-82-1
(S)-3-Eth-(Z)-ylidene-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione

Guidance literature:: Yield given; Multistep reaction;
DOI:10.1016/S0040-4039(98)01599-8

Reference yield:

: 75-07-0,9002-91-9
acetaldehyde

: 114604-94-3
(8αS)-(1,4-dioxo-octahydro-pyrrolo[1,2-a]pyrazin-3-yl)-phosphonic acid dimethyl ester

: 114604-88-5,160706-82-1
(S)-3-Eth-(E)-ylidene-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione

: 114604-89-6,160706-82-1
(S)-3-Eth-(Z)-ylidene-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione

Guidance literature:: With potassium tert-butylate; Product distribution; 1.) -70 deg C, CH₂Cl₂, 10 min; 2.) -70 deg C to RT; various aldehydes;
DOI:10.1016/S0040-4039(00)96483-9