1,3-phenyldimethyl-bis-(2-<(1,5-dideoxy-3,4-dimethyl-5-oxo-2H-pyrrole-2-ylidene methyl)-4-methyl-1H-pyrrole-3-propanoic acid dimethyl ester>)

Base Information

• Chemical Name: 1,3-phenyldimethyl-bis-(2-<(1,5-dideoxy-3,4-dimethyl-5-oxo-2H-pyrrole-2-ylidene methyl)-4-methyl-1H-pyrrole-3-propanoic acid dimethyl ester>)
• CAS No.: 157670-02-5
• Molecular Formula: C₄₀H₄₆N₄O₆
• Molecular Weight: 678.828
• Mol file: 157670-02-5.mol

Synonyms:1,3-phenyldimethyl-bis-(2-<(1,5-dideoxy-3,4-dimethyl-5-oxo-2H-pyrrole-2-ylidene methyl)-4-methyl-1H-pyrrole-3-propanoic acid dimethyl ester>)

Chemical Property of 1,3-phenyldimethyl-bis-(2-<(1,5-dideoxy-3,4-dimethyl-5-oxo-2H-pyrrole-2-ylidene methyl)-4-methyl-1H-pyrrole-3-propanoic acid dimethyl ester>)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3-phenyldimethyl-bis-(2-<(1,5-dideoxy-3,4-dimethyl-5-oxo-2H-pyrrole-2-ylidene methyl)-4-methyl-1H-pyrrole-3-propanoic acid dimethyl ester>)

There total 7 articles about 1,3-phenyldimethyl-bis-(2-<(1,5-dideoxy-3,4-dimethyl-5-oxo-2H-pyrrole-2-ylidene methyl)-4-methyl-1H-pyrrole-3-propanoic acid dimethyl ester>) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

1,3-phenyldimethylene-bis-(2-<5-(1,5-dideoxy-3,4-dimethyl-5-oxo-2H-pyrrole-2-ylidene methyl)-4-methyl-2H-pyrrole-3-propanoic acid methyl ester>) → 1,3-phenyldimethyl-bis-(2-<(1,5-dideoxy-3,4-dimethyl-5-oxo-2H-pyrrole-2-ylidene methyl)-4-methyl-1H-pyrrole-3-propanoic acid dimethyl ester>) (157670-02-5)

Guidance literature:

With sodium tetrahydroborate; In tetrahydrofuran; methanol; for 2h; sonication;

DOI:10.1016/S0040-4020(01)85333-3

Reference yield:

3,4-dimethyl-1H-pyrrole (822-51-5) → 1,3-phenyldimethyl-bis-(2-<(1,5-dideoxy-3,4-dimethyl-5-oxo-2H-pyrrole-2-ylidene methyl)-4-methyl-1H-pyrrole-3-propanoic acid dimethyl ester>) (157670-02-5)

Guidance literature:

Multi-step reaction with 5 steps

1: 95 percent / H₂O₂ / pyridine

2: 90 percent / aq. potassium hydroxide / methanol / Ambient temperature

3: 100 percent / diethyl ether; methanol / 1 h

4: 53 percent / trifluoroacetic acid / 2.5 h / 70 °C

5: 94 percent / sodium borohydride / methanol; tetrahydrofuran / 2 h / sonication

With potassium hydroxide; sodium tetrahydroborate; dihydrogen peroxide; trifluoroacetic acid; In tetrahydrofuran; pyridine; methanol; diethyl ether;

DOI:10.1016/S0040-4020(01)85333-3

Reference yield:

3,4-dimethyl-3-pyrrolin-2-one (4030-22-2) → 1,3-phenyldimethyl-bis-(2-<(1,5-dideoxy-3,4-dimethyl-5-oxo-2H-pyrrole-2-ylidene methyl)-4-methyl-1H-pyrrole-3-propanoic acid dimethyl ester>) (157670-02-5)

Guidance literature:

Multi-step reaction with 4 steps

1: 90 percent / aq. potassium hydroxide / methanol / Ambient temperature

2: 100 percent / diethyl ether; methanol / 1 h

3: 53 percent / trifluoroacetic acid / 2.5 h / 70 °C

4: 94 percent / sodium borohydride / methanol; tetrahydrofuran / 2 h / sonication

With potassium hydroxide; sodium tetrahydroborate; trifluoroacetic acid; In tetrahydrofuran; methanol; diethyl ether;

DOI:10.1016/S0040-4020(01)85333-3

upstream raw materials:

3,4-dimethyl-1H-pyrrole

3,4-dimethyl-3-pyrrolin-2-one

3,4-dimethyl-1H-pyrrole-2-carboxylic acid ethyl ester

Isophthalaldehyde