N-Boc-O-acetyl-DOPA methyl ester

Base Information

• Chemical Name: N-Boc-O-acetyl-DOPA methyl ester
• CAS No.: 1240789-51-8
• Molecular Formula: C₁₉H₂₅NO₈
• Molecular Weight: 395.409
• Mol file: 1240789-51-8.mol

Synonyms:N-Boc-O-acetyl-DOPA methyl ester

Chemical Property of N-Boc-O-acetyl-DOPA methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N-Boc-O-acetyl-DOPA methyl ester

There total 1 articles about N-Boc-O-acetyl-DOPA methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methyl (S)-2-(tert-butoxycarbonylamino)-3-(3,4-dihydroxyphenyl)propanoate (37169-36-1) + acetic anhydride (108-24-7) → N-Boc-O-acetyl-DOPA methyl ester (1240789-51-8)

Guidance literature:

With pyridine; at 0 - 23 ℃; for 7h;

DOI:10.1021/ja105834t

Reference yield: 60.0%

N-Boc-O-acetyl-DOPA methyl ester (1240789-51-8) → N-Boc-O-acetyl-6-iodo-DOPA methyl ester (1240789-52-9)

Guidance literature:

With iodine; bis-[(trifluoroacetoxy)iodo]benzene; In dichloromethane; at 0 - 23 ℃; for 7h;

DOI:10.1021/ja105834t

upstream raw materials:

methyl (S)-2-(tert-butoxycarbonylamino)-3-(3,4-dihydroxyphenyl)propanoate

acetic anhydride

Downstream raw materials:

N-Boc-O-acetyl-6-iodo-DOPA methyl ester