Diethyl <(3-Phenylprop-2-enylidene)amino>(pyridin-2-yl)methylphosphonate

Base Information

• Chemical Name: Diethyl <(3-Phenylprop-2-enylidene)amino>(pyridin-2-yl)methylphosphonate
• CAS No.: 128474-61-3
• Molecular Formula: C₁₉H₂₃N₂O₃P
• Molecular Weight: 358.377
• Mol file: 128474-61-3.mol

Synonyms:Diethyl <(3-Phenylprop-2-enylidene)amino>(pyridin-2-yl)methylphosphonate

Chemical Property of Diethyl <(3-Phenylprop-2-enylidene)amino>(pyridin-2-yl)methylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Diethyl <(3-Phenylprop-2-enylidene)amino>(pyridin-2-yl)methylphosphonate

There total 2 articles about Diethyl <(3-Phenylprop-2-enylidene)amino>(pyridin-2-yl)methylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(E)-3-phenylpropenal (14371-10-9) + Diethyl Amino(pyridin-2-yl)methylphosphonate (128474-60-2) → Diethyl <(3-Phenylprop-2-enylidene)amino>(pyridin-2-yl)methylphosphonate (128474-61-3)

Guidance literature:

In dichloromethane; for 5h; Heating;

DOI:10.1002/hlca.19900730121

Reference yield:

(Benzylamino-pyridin-2-yl-methyl)-phosphonic acid diethyl ester; hydrochloride (128474-66-8) → Diethyl <(3-Phenylprop-2-enylidene)amino>(pyridin-2-yl)methylphosphonate (128474-61-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / cyclohexene, PdCl₂ / ethanol / 20 h / Heating

2: 99 percent / CH₂Cl₂ / 5 h / Heating

With palladium dichloride; cyclohexene; In ethanol; dichloromethane;

DOI:10.1002/hlca.19900730121

Reference yield: 80.0%

2-azidoacetyl chloride (30426-58-5) + Diethyl <(3-Phenylprop-2-enylidene)amino>(pyridin-2-yl)methylphosphonate (128474-61-3) → Diethyl (cis-3-Azido-2-oxo-4-styrylazetidin-1-yl)(pyridin-2-yl)methylphosphonate

Guidance literature:

With triethylamine; In dichloromethane; at -10 ℃; for 2.5h;

DOI:10.1002/hlca.19900730121

upstream raw materials:

(E)-3-phenylpropenal

Diethyl Amino(pyridin-2-yl)methylphosphonate

(Benzylamino-pyridin-2-yl-methyl)-phosphonic acid diethyl ester; hydrochloride