5-(2,2,2-Trifluoro-ethoxy)-quinazol ine-2,4-diamine

Base Information

Chemical Name:5-(2,2,2-Trifluoro-ethoxy)-quinazol ine-2,4-diamine
CAS No.:119584-82-6
Molecular Formula:C₁₀H₉F₃N₄O
Molecular Weight:258.203
Hs Code.:
Mol file:119584-82-6.mol

Synonyms:5-(2,2,2-Trifluoroethoxy)quinazoline-2,4-diamine

Suppliers and Price of 5-(2,2,2-Trifluoro-ethoxy)-quinazol ine-2,4-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 5-(2,2,2-Trifluoro-ethoxy)-quinazol ine-2,4-diamine

Chemical Property:

PSA：88.51000
LogP:1.59550

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-(2,2,2-Trifluoro-ethoxy)-quinazol ine-2,4-diamine

There total 3 articles about 5-(2,2,2-Trifluoro-ethoxy)-quinazol ine-2,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 124-46-9,20734-13-8,100224-74-6,593-85-1,90332-86-8,3425-08-9
guanidine hydrogen carbonate

: 119584-74-6
2-fluoro-6-(2,2,2-trifluoroethoxy)benzonitrile

: 119584-82-6
5-(2,2,2-trifluoroethoxy)-2,4-diaminoquinazoline

Guidance literature:: In N,N-dimethyl acetamide; at 140 - 142 ℃; for 6h;

Reference yield:

: 1897-52-5
2,6 difluorobenzonitrile

: 119584-82-6
5-(2,2,2-trifluoroethoxy)-2,4-diaminoquinazoline

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / Cs₂CO₃ / N,N-dimethyl-acetamide / 24 h / Ambient temperature

2: 79 percent / N,N-dimethyl-acetamide / 6 h / 140 - 142 °C

With caesium carbonate; In N,N-dimethyl acetamide;