1-Azabicyclo[2.2.1]heptane-4-carboxamide

Base Information

Chemical Name:1-Azabicyclo[2.2.1]heptane-4-carboxamide
CAS No.:119103-03-6
Molecular Formula:C₇H₁₂N₂O
Molecular Weight:140.185
Hs Code.:
DSSTox Substance ID:DTXSID70576505
Wikidata:Q82466238
Mol file:119103-03-6.mol

Synonyms:1-AZABICYCLO[2.2.1]HEPTANE-4-CARBOXAMIDE;119103-03-6;1-Azabicyclo[2.2.1]heptane-4-carboxamide(9CI);SCHEMBL9050123;DTXSID70576505;AKOS006339653

Suppliers and Price of 1-Azabicyclo[2.2.1]heptane-4-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-Azabicyclo[2.2.1]heptane-4-carboxamide

Chemical Property:

Boiling Point:301.9±21.0 °C(Predicted)
PKA:16.60±0.20(Predicted)
PSA：47.32000
Density:1.21±0.1 g/cm3(Predicted)
LogP:0.65510
XLogP3:-0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:140.094963011
Heavy Atom Count:10
Complexity:170

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN2CCC1(C2)C(=O)N

Technology Process of 1-Azabicyclo[2.2.1]heptane-4-carboxamide

There total 3 articles about 1-Azabicyclo[2.2.1]heptane-4-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 119102-24-8
ethyl 1-azabicyclo<2.2.1>hept-4-yl carboxylate

: 119103-03-6
1-azabicyclo[2.2.1]hept-4-yl carboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: aq. HCl / 17 h / Heating

2: SOCl₂ / 4.25 h / Heating

3: ammonia / CH₂Cl₂ / -40 - 20 °C

With hydrogenchloride; thionyl chloride; ammonia; In dichloromethane;
DOI:10.1021/jm00091a007

Reference yield:

: 133643-09-1
1-Aza-bicyclo[2.2.1]heptane-4-carbonyl chloride; hydrochloride

: 119103-03-6
1-azabicyclo[2.2.1]hept-4-yl carboxamide

Guidance literature:: With ammonia; In dichloromethane; at -40 - 20 ℃; Yield given;
DOI:10.1021/jm00091a007

Reference yield:

: 119102-95-3
1-Aza-bicyclo[2.2.1]heptane-4-carboxylic acid; hydrochloride

: 119103-03-6
1-azabicyclo[2.2.1]hept-4-yl carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / 4.25 h / Heating

2: ammonia / CH₂Cl₂ / -40 - 20 °C

With thionyl chloride; ammonia; In dichloromethane;
DOI:10.1021/jm00091a007