Technology Process of C38H43N2O9P
There total 3 articles about C38H43N2O9P which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
4 A molecular sieve; boron trifluoride diethyl etherate;
In
dichloromethane;
at -23 ℃;
for 6h;
DOI:10.1016/S0040-4039(00)01343-5
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 66 percent / NaOAc / PdCl2 / acetic acid; H2O / 2 h / 80 °C
2: 70 percent / n-BuLi; HMPA / tetrahydrofuran / 2.5 h / -78 - -30 °C
3: 80 percent / BF3*OEt2; molecular sieves 4 Angstroem / CH2Cl2 / 6 h / -23 °C
With
N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; 4 A molecular sieve; boron trifluoride diethyl etherate; sodium acetate;
palladium dichloride;
In
tetrahydrofuran; dichloromethane; water; acetic acid;
1: Substitution / 2: Substitution / 3: Isomerization;
DOI:10.1016/S0040-4039(00)01343-5
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 70 percent / n-BuLi; HMPA / tetrahydrofuran / 2.5 h / -78 - -30 °C
2: 80 percent / BF3*OEt2; molecular sieves 4 Angstroem / CH2Cl2 / 6 h / -23 °C
With
N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; 4 A molecular sieve; boron trifluoride diethyl etherate;
In
tetrahydrofuran; dichloromethane;
1: Substitution / 2: Isomerization;
DOI:10.1016/S0040-4039(00)01343-5