benzyl 2(R)-<5(R)-ethyl-3(R)-methyl-5-<5(R)-hydroxy-6(R)-methyl-2(S)-tetrahydropyranyl>-2(R)-tetrahydrofuryl>butyl ether

Base Information

Chemical Name:benzyl 2(R)-<5(R)-ethyl-3(R)-methyl-5-<5(R)-hydroxy-6(R)-methyl-2(S)-tetrahydropyranyl>-2(R)-tetrahydrofuryl>butyl ether
CAS No.:87678-35-1
Molecular Formula:C₂₄H₃₈O₄
Molecular Weight:390.563
Hs Code.:

Synonyms:benzyl 2(R)-<5(R)-ethyl-3(R)-methyl-5-<5(R)-hydroxy-6(R)-methyl-2(S)-tetrahydropyranyl>-2(R)-tetrahydrofuryl>butyl ether

Suppliers and Price of benzyl 2(R)-<5(R)-ethyl-3(R)-methyl-5-<5(R)-hydroxy-6(R)-methyl-2(S)-tetrahydropyranyl>-2(R)-tetrahydrofuryl>butyl ether

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of benzyl 2(R)-<5(R)-ethyl-3(R)-methyl-5-<5(R)-hydroxy-6(R)-methyl-2(S)-tetrahydropyranyl>-2(R)-tetrahydrofuryl>butyl ether

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of benzyl 2(R)-<5(R)-ethyl-3(R)-methyl-5-<5(R)-hydroxy-6(R)-methyl-2(S)-tetrahydropyranyl>-2(R)-tetrahydrofuryl>butyl ether

There total 5 articles about benzyl 2(R)-<5(R)-ethyl-3(R)-methyl-5-<5(R)-hydroxy-6(R)-methyl-2(S)-tetrahydropyranyl>-2(R)-tetrahydrofuryl>butyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 87678-34-0
benzyl 2(R)-<5(R)-ethyl-3(R)-methyl-5-<5(R)-(methoxymethoxy)-6(R)-methyl-2(S)-tetrahydropyranyl>-2(R)-tetrahydrofuryl>butyl ether

: 87678-35-1
benzyl 2(R)-<5(R)-ethyl-3(R)-methyl-5-<5(R)-hydroxy-6(R)-methyl-2(S)-tetrahydropyranyl>-2(R)-tetrahydrofuryl>butyl ether

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; at 50 ℃; for 12h; Yield given;
DOI:10.1021/jo00174a008

Reference yield:

: 87678-33-9
benzyl 2(R)-<5(S)-vinyl-3(R)-methyl-5-<5(R)-(methoxymethoxy)-6(R)-methyl-2(S)-tetrahydropyranyl>-2(R)-tetrahydrofuryl>butyl ether

: 87678-35-1
benzyl 2(R)-<5(R)-ethyl-3(R)-methyl-5-<5(R)-hydroxy-6(R)-methyl-2(S)-tetrahydropyranyl>-2(R)-tetrahydrofuryl>butyl ether

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / H₂ / W-2 Raney nickel catalyst / ethyl acetate / 12 h

2: 10percent aq. HCl / tetrahydrofuran / 12 h / 50 °C

With hydrogenchloride; hydrogen; W-2 Raney nickel catalyst; In tetrahydrofuran; ethyl acetate;
DOI:10.1021/jo00174a008

Reference yield:

: 87678-32-8
benzyl 2(R)-<5(R)-formyl-3(R)-methyl-5-<5(R)-(methoxymethoxy)-6(R)-methyl-2(S)-tetrahydropyranyl>-2(R)-tetrahydrofuryl>butyl ether

: 87678-35-1
benzyl 2(R)-<5(R)-ethyl-3(R)-methyl-5-<5(R)-hydroxy-6(R)-methyl-2(S)-tetrahydropyranyl>-2(R)-tetrahydrofuryl>butyl ether

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) n-butyllithium / 1.) THF, hexane, -78 deg C, then room temp., 1 h, 2.) THF, -78 deg C, then room temp., 10 h

2: 97 percent / H₂ / W-2 Raney nickel catalyst / ethyl acetate / 12 h

3: 10percent aq. HCl / tetrahydrofuran / 12 h / 50 °C

With hydrogenchloride; n-butyllithium; hydrogen; W-2 Raney nickel catalyst; In tetrahydrofuran; ethyl acetate;
DOI:10.1021/jo00174a008