4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-(tert-butyl-dimethyl-silanyloxymethyl)-oxazole

Base Information

Chemical Name:4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-(tert-butyl-dimethyl-silanyloxymethyl)-oxazole
CAS No.:633305-43-8
Molecular Formula:C₄₆H₇₃NO₆Si₃
Molecular Weight:820.345
Hs Code.:

4-(4-(<i>tert</i>-butyl-dimethyl-silanyloxy)-6-{6-[2-(<i>tert</i>-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-(<i>tert</i>-butyl-dimethyl-silanyloxymethyl)-oxazole

Synonyms:4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-(tert-butyl-dimethyl-silanyloxymethyl)-oxazole

Suppliers and Price of 4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-(tert-butyl-dimethyl-silanyloxymethyl)-oxazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-(tert-butyl-dimethyl-silanyloxymethyl)-oxazole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-(tert-butyl-dimethyl-silanyloxymethyl)-oxazole

There total 9 articles about 4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-(tert-butyl-dimethyl-silanyloxymethyl)-oxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 633305-60-9
methanesulfonic acid 1-{4-(tert-butyl-dimethyl-silanyloxy)-6-[2-(tert-butyl-dimethyl-silanyloxymethyl)-oxazol-4-yl]-tetrahydro-pyran-2-ylmethyl}-3-[4-(tert-butyl-diphenyl-silanyloxy)-2-hydroxy-butyl]-but-3-enyl ester

: 633305-43-8
4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-(tert-butyl-dimethyl-silanyloxymethyl)-oxazole

Guidance literature:: With triethylamine; In acetonitrile; for 12h; Heating;
DOI:10.1055/s-2003-41462

Reference yield:

: 633305-66-5
(R)-tert-butyl-(3-(4-methoxybenzyloxy)hex-5-enyloxy)-diphenylsilane

: 633305-43-8
4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-(tert-butyl-dimethyl-silanyloxymethyl)-oxazole

Guidance literature:: Multi-step reaction with 9 steps

1.1: 86 percent / aq. CuCl; oxygen / PdCl₂ / dimethylformamide / 12 h / 20 °C

2.1: LiHMDS / tetrahydrofuran / -78 °C

3.1: TiCl₄ / tetrahydrofuran / 0.5 h / -78 °C

3.2: 334 mg / tetrahydrofuran / 2 h / -78 °C

4.1: DMAP; pyridine / 3 h / 20 °C

5.1: 411 mg / 4 Angstroem molecular sieves; TiCl₄ / tetrahydrofuran / 3.25 h / 0 - 20 °C

6.1: DIBAL / CH₂Cl₂; toluene / 1 h / -78 °C

7.1: Et₃N / CH₂Cl₂ / 0.5 h / 0 °C

8.1: 32 mg / DDQ / CH₂Cl₂ / 2 h / 20 °C / pH 7

9.1: 83 percent / Et₃N / acetonitrile / 24 h / Heating

With pyridine; dmap; 4 A molecular sieve; oxygen; titanium tetrachloride; diisobutylaluminium hydride; triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; copper(l) chloride; lithium hexamethyldisilazane; palladium dichloride; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene; acetonitrile; 1.1: Wacker oxidation;
DOI:10.1002/chem.200500892

Reference yield:

: 633305-55-2
6-(tert-butyl-diphenyl-silanyloxy)-4-(4-methoxy-benzyloxy)-hexan-2-one

: 633305-43-8
4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-(tert-butyl-dimethyl-silanyloxymethyl)-oxazole

Guidance literature:: Multi-step reaction with 8 steps

1.1: LiHMDS / tetrahydrofuran / -78 °C

2.1: TiCl₄ / tetrahydrofuran / 0.5 h / -78 °C

2.2: 334 mg / tetrahydrofuran / 2 h / -78 °C

3.1: DMAP; pyridine / 3 h / 20 °C

4.1: 411 mg / 4 Angstroem molecular sieves; TiCl₄ / tetrahydrofuran / 3.25 h / 0 - 20 °C

5.1: DIBAL / CH₂Cl₂; toluene / 1 h / -78 °C

6.1: Et₃N / CH₂Cl₂ / 0.5 h / 0 °C

7.1: 32 mg / DDQ / CH₂Cl₂ / 2 h / 20 °C / pH 7

8.1: 83 percent / Et₃N / acetonitrile / 24 h / Heating

With pyridine; dmap; 4 A molecular sieve; titanium tetrachloride; diisobutylaluminium hydride; triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; lithium hexamethyldisilazane; In tetrahydrofuran; dichloromethane; toluene; acetonitrile;
DOI:10.1002/chem.200500892