4-AMINOBENZOIC-2,6-D2 ACID

Base Information

• Chemical Name: 4-AMINOBENZOIC-2,6-D2 ACID
• CAS No.: 118872-62-1
• Molecular Formula: C₇H₇NO₂
• Molecular Weight: 139.122
• Mol file: 118872-62-1.mol

Synonyms:Benzoic-2,6-d2acid, p-amino- (6CI)

Chemical Property of 4-AMINOBENZOIC-2,6-D2 ACID

Chemical Property:

• Melting Point: 186-186.5 °C
• PSA: 63.32000
• LogP: 1.54820

Purity/Quality:

≥95%; ≥98% atom D ^*data from raw suppliers

4-Aminobenzoic-2,6-d2Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: The preparation and synthesis of deuteriated organic compound, 4-Aminobenzoic-2,6-d2 Acid. It is reported as a stable isotope-labeled folate internal standard for the measurement of red blood cell folates using gas chromatography-mass spectrometry.

Technology Process of 4-AMINOBENZOIC-2,6-D2 ACID

There total 2 articles about 4-AMINOBENZOIC-2,6-D2 ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-amino-benzoic acid (150-13-0,159246-81-8,8014-65-1) → 4-amino-2,6-dideuterio-benzoic acid (118872-62-1)

Guidance literature:

With water-d2; η4-1,5-cyclooctadiene-μ-2,4-pentanedionato-iridium(I); In N,N-dimethyl acetamide; at 90 ℃; for 2.25h; Further Variations:; Catalysts; Temperatures; microwave irradiation; reaction times; Product distribution;

DOI:10.1002/jlcr.780

Reference yield:

→ 4-amino-2,6-dideuterio-benzoic acid (118872-62-1)

Guidance literature:

4-Nitrobenzoesaeure-2,6-d(2), Sn, HCl;

DOI:10.1139/v61-003

upstream raw materials:

4-amino-benzoic acid