2H-Cyclopenta[b]furan-3-ol,hexahydro-,acetate,(3-alpha-,3a-alpha-,6a-alpha-)-(9CI)

Base Information

• Chemical Name: 2H-Cyclopenta[b]furan-3-ol,hexahydro-,acetate,(3-alpha-,3a-alpha-,6a-alpha-)-(9CI)
• CAS No.: 118867-24-6
• Molecular Formula: C₉H₁₄O₃
• Molecular Weight: 170.208
• Mol file: 118867-24-6.mol

Synonyms:2H-Cyclopenta[b]furan-3-ol,hexahydro-,acetate,(3-alpha-,3a-alpha-,6a-alpha-)-(9CI)

Chemical Property of 2H-Cyclopenta[b]furan-3-ol,hexahydro-,acetate,(3-alpha-,3a-alpha-,6a-alpha-)-(9CI)

Chemical Property:

• Boiling Point: 70 - 72 °C (0.2 mmHg)
• PSA: 35.53000
• LogP: 1.11700

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2H-Cyclopenta[b]furan-3-ol,hexahydro-,acetate,(3-alpha-,3a-alpha-,6a-alpha-)-(9CI)

There total 3 articles about 2H-Cyclopenta[b]furan-3-ol,hexahydro-,acetate,(3-alpha-,3a-alpha-,6a-alpha-)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetoxyacetyl cyclopentanone (118790-18-4) → Acetic acid (3aR,6aS)-(hexahydro-cyclopenta[b]furan-3-yl) ester (118790-25-3,118867-24-6)

Guidance literature:

Multi-step reaction with 3 steps

1: H₂ / Raney nickel W₄ / ethanol / 6 h / 60 °C / 76000.1 Torr

2: acetyl chloride, ethanol / 3 h / Heating

3: pyridine

With pyridine; ethanol; hydrogen; acetyl chloride; Raney nickel W₄; In ethanol;

Reference yield:

Acetic acid 2-hydroxy-2-(2-hydroxy-cyclopentyl)-ethyl ester (118790-20-8) → Acetic acid (3aR,6aS)-(hexahydro-cyclopenta[b]furan-3-yl) ester (118790-25-3,118867-24-6)

Guidance literature:

Multi-step reaction with 2 steps

1: acetyl chloride, ethanol / 3 h / Heating

2: pyridine

With pyridine; ethanol; acetyl chloride;

Reference yield:

acetic anhydride (108-24-7) + perhydrocyclopentafuranne-cis ol-3-endo (116154-86-0,118867-18-8,118867-19-9) → Acetic acid (3aR,6aS)-(hexahydro-cyclopenta[b]furan-3-yl) ester (118790-25-3,118867-24-6)

Guidance literature:

With pyridine; Yield given;

upstream raw materials:

acetic anhydride

perhydrocyclopentafuranne-cis ol-3-endo

Acetic acid 2-hydroxy-2-(2-hydroxy-cyclopentyl)-ethyl ester

acetoxyacetyl cyclopentanone