Technology Process of 5-{[(3R)-3-{[tert-butyl(diphenyl)silyl]oxy}butyl]sulfonyl}-1-phenyl-1H-tetrazole
There total 5 articles about 5-{[(3R)-3-{[tert-butyl(diphenyl)silyl]oxy}butyl]sulfonyl}-1-phenyl-1H-tetrazole which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hexaammonium heptamolybdate tetrahydrate; dihydrogen peroxide;
In
ethanol;
at 0 - 20 ℃;
for 6h;
Inert atmosphere;
DOI:10.1002/hlca.201500267
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1H-imidazole
2: water; 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane
3: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / -20 - 0 °C
4: hexaammonium heptamolybdate tetrahydrate; dihydrogen peroxide / ethanol / 6 h / 0 - 20 °C
With
1H-imidazole; hexaammonium heptamolybdate tetrahydrate; di-isopropyl azodicarboxylate; water; dihydrogen peroxide; triphenylphosphine; 2,3-dicyano-5,6-dichloro-p-benzoquinone;
In
tetrahydrofuran; ethanol; dichloromethane;
3: Mitsunobu reaction;
DOI:10.1002/ejoc.201200241
- Guidance literature:
-
Multi-step reaction with 2 steps
1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / -20 - 0 °C
2: hexaammonium heptamolybdate tetrahydrate; dihydrogen peroxide / ethanol / 6 h / 0 - 20 °C
With
hexaammonium heptamolybdate tetrahydrate; di-isopropyl azodicarboxylate; dihydrogen peroxide; triphenylphosphine;
In
tetrahydrofuran; ethanol;
1: Mitsunobu reaction;
DOI:10.1002/ejoc.201200241
