SARCOSINE-METHYL-D3

Base Information

• Chemical Name: SARCOSINE-METHYL-D3
• CAS No.: 118685-91-9
• Molecular Formula: C₃H₇NO₂
• Molecular Weight: 92.0703
• Mol file: 118685-91-9.mol

Synonyms:Sarcosine-methyl-d3(6CI); [2H3]Sarcosine

Chemical Property of SARCOSINE-METHYL-D3

Chemical Property:

• Vapor Pressure: 0.184mmHg at 25°C
• Melting Point: 208 °C (dec.)(lit.)
• Refractive Index: 1.431
• Boiling Point: 195.1°C at 760 mmHg
• Flash Point: 71.8°C
• PSA: 49.33000
• Density: 1.13g/cm³
• LogP: -0.31870

Purity/Quality:

98%min ^*data from raw suppliers

Sarcosine-d3 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Sarcosine-d3 is the labelled analog of Sarcosine (S140500). Sarcosine is a type?1 glycine transporter inhibitor and a glycine agonist that may be useful for treating schizophrenia (1). Sarcosine is also a marker for prostate cancer bioagression (2). Sarcosine-d3 is also an intermediate in the synthesis of Creatinine-d3 (C781502), which is a Labelled Creatinine. The end product of creatine catabolism. Normal constituent of urine. Also found together with creatine in muscle tissues and blood. Occurs in all soils and in grain seeds and other vegetable matter. Has been found in certain fish and in crab meat extract.

Technology Process of SARCOSINE-METHYL-D3

There total 2 articles about SARCOSINE-METHYL-D3 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

N-tosylsarcosine-4,4,4-d3 (35009-46-2) → N-(CD3)-glycine (118685-91-9)

Guidance literature:

With hydrogenchloride; In water; at 100 ℃; for 14h;

Reference yield:

N-Tosylglycine (1080-44-0) → N-(CD3)-glycine (118685-91-9)

Guidance literature:

With sodium hydroxide; Erhitzen des Reaktionsprodukts mit konz.wss.HCl;

upstream raw materials:

N-Tosylglycine

N-tosylsarcosine-4,4,4-d3

Refernces