5-(Diphenyl-phosphinoyl)-7-hydroxy-4-oxo-7-phenyl-heptanoic acid methyl ester

Base Information

Chemical Name:5-(Diphenyl-phosphinoyl)-7-hydroxy-4-oxo-7-phenyl-heptanoic acid methyl ester
CAS No.:105445-38-3
Molecular Formula:C₂₆H₂₇O₅P
Molecular Weight:450.471
Hs Code.:

Synonyms:5-(Diphenyl-phosphinoyl)-7-hydroxy-4-oxo-7-phenyl-heptanoic acid methyl ester

Suppliers and Price of 5-(Diphenyl-phosphinoyl)-7-hydroxy-4-oxo-7-phenyl-heptanoic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 5-(Diphenyl-phosphinoyl)-7-hydroxy-4-oxo-7-phenyl-heptanoic acid methyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Technology Process of 5-(Diphenyl-phosphinoyl)-7-hydroxy-4-oxo-7-phenyl-heptanoic acid methyl ester

There total 3 articles about 5-(Diphenyl-phosphinoyl)-7-hydroxy-4-oxo-7-phenyl-heptanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: Succinic acid 3-(diphenyl-phosphinoyl)-1-phenyl-propyl ester methyl ester

: 105445-38-3
5-(Diphenyl-phosphinoyl)-7-hydroxy-4-oxo-7-phenyl-heptanoic acid methyl ester

Guidance literature:: With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃;
DOI:10.1016/S0040-4039(00)83991-X

Reference yield:

: 22950-48-7
3-diphenylphosphinoyl-1-phenylpropan-1-ol

: 105445-38-3
5-(Diphenyl-phosphinoyl)-7-hydroxy-4-oxo-7-phenyl-heptanoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / 4-dimethylaminopyridine

2: 79 percent / LDA / tetrahydrofuran / -78 °C

With lithium diisopropyl amide; dmap; In tetrahydrofuran;
DOI:10.1016/S0040-4039(00)83991-X

Reference yield:

: 1490-25-1
succinic acid monomethylester chloride

: 105445-38-3
5-(Diphenyl-phosphinoyl)-7-hydroxy-4-oxo-7-phenyl-heptanoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / 4-dimethylaminopyridine

2: 79 percent / LDA / tetrahydrofuran / -78 °C

With lithium diisopropyl amide; dmap; In tetrahydrofuran;
DOI:10.1016/S0040-4039(00)83991-X