3-(6-Chloro-pyridin-3-yl)-acrylic acid

Base Information

Chemical Name:3-(6-Chloro-pyridin-3-yl)-acrylic acid
CAS No.:118420-00-1
Molecular Formula:C₈H₆ClNO₂
Molecular Weight:183.594
Hs Code.:2933399990
DSSTox Substance ID:DTXSID50698714
Mol file:118420-00-1.mol

Synonyms:3-(6-chloro-pyridin-3-yl)-acrylic acid;DTXSID50698714;NOCOZQLIBKEIAJ-UHFFFAOYSA-N;AKOS026729432;SB54685;3-(6-chloropyridine-3-yl)acrylic acid

Suppliers and Price of 3-(6-Chloro-pyridin-3-yl)-acrylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
3-(6-Chloropyridin-3-yl)-acrylic acid 95%+
1g
$ 816.00

Labseeker
2-propenoicacid,3-(6-chloro-3-pyridinyl)-,(E)- 95
10g
$ 1150.00

Crysdot
(E)-3-(6-Chloropyridin-3-yl)acrylicacid 95+%
1g
$ 589.00

Chemenu
(E)-3-(6-Chloropyridin-3-yl)acrylicacid 95%
1g
$ 557.00

Biosynth Carbosynth
(E)-3-(6-Chloropyridin-3-yl)acrylic acid
5 g
$ 3000.00

Apolloscientific
3-(6-Chloropyridin-3-yl)acrylic acid
1g
$ 539.00

American Custom Chemicals Corporation
2-PROPENOIC ACID, 3-(6-CHLORO-3-PYRIDINYL)-, (E)- 95.00%
10G
$ 4498.73

American Custom Chemicals Corporation
2-PROPENOIC ACID, 3-(6-CHLORO-3-PYRIDINYL)-, (E)- 95.00%
5G
$ 3054.98

Alichem
(E)-3-(6-Chloropyridin-3-yl)acrylicacid
1g
$ 499.20

Advanced Chemicals Intermediatesced Chemicals Intermediates
3-(6-Chloro-pyridin-3-yl)-acrylicacid 95%+
5g
$ 1297.75

Total 12 raw suppliers

Chemical Property of 3-(6-Chloro-pyridin-3-yl)-acrylic acid

Chemical Property:

PSA：50.19000
LogP:1.83280
Storage Temp.:2-8°C
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:183.0087061
Heavy Atom Count:12
Complexity:194

Purity/Quality:

97% ^*data from raw suppliers

3-(6-Chloropyridin-3-yl)-acrylic acid 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=NC=C1C=CC(=O)O)Cl

Technology Process of 3-(6-Chloro-pyridin-3-yl)-acrylic acid

There total 5 articles about 3-(6-Chloro-pyridin-3-yl)-acrylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4548-45-2
2-chloro-5-nitropyridine

: 118420-00-1
(E)-3-(6-chloro-3-pyridyl)prop-2-enoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogen / 5 percent Pd/C / methanol / 760 Torr / Ambient temperature

2: 1.) NaNO₂, conc. HCl, 2.) Cu₂O / 1.) acetone, methanol, water, 5 deg C, 2.) 35 deg C

3: 4 N KOH / ethanol / Heating

With copper(I) oxide; hydrogenchloride; potassium hydroxide; hydrogen; sodium nitrite; palladium on activated charcoal; In methanol; ethanol;
DOI:10.1021/jm00123a012