(R)-tert-butyl 2-((S)-amino(3-fluoro-4-methoxyphenyl)methyl)pyrrolidine-1-carboxylate

Base Information

• Chemical Name: (R)-tert-butyl 2-((S)-amino(3-fluoro-4-methoxyphenyl)methyl)pyrrolidine-1-carboxylate
• CAS No.: 1422188-01-9
• Molecular Formula: C₁₇H₂₅FN₂O₃
• Molecular Weight: 324.396

Synonyms:(R)-tert-butyl 2-((S)-amino(3-fluoro-4-methoxyphenyl)methyl)pyrrolidine-1-carboxylate

Chemical Property of (R)-tert-butyl 2-((S)-amino(3-fluoro-4-methoxyphenyl)methyl)pyrrolidine-1-carboxylate

Chemical Property:

Purity/Quality:

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Technology Process of (R)-tert-butyl 2-((S)-amino(3-fluoro-4-methoxyphenyl)methyl)pyrrolidine-1-carboxylate

There total 1 articles about (R)-tert-butyl 2-((S)-amino(3-fluoro-4-methoxyphenyl)methyl)pyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (R)-tert-butyl 2-((S)-amino(3-fluoro-4-methoxyphenyl)methyl)pyrrolidine-1-carboxylate (1422188-01-9)

Guidance literature:

With hydrazine hydrate; In tetrahydrofuran; methanol; at 20 ℃; for 48h;

Reference yield: 47.0%

C14H14FN3O3*ClH + (R)-tert-butyl 2-((S)-amino(3-fluoro-4-methoxyphenyl)methyl)pyrrolidine-1-carboxylate (1422188-01-9) → C31H37F2N5O5 (1437787-43-3)

Guidance literature:

C₁₄H₁₄FN₃O₃*ClH; With 1,1'-carbonyldiimidazole; In dichloromethane; at 20 ℃; for 1h; Inert atmosphere;

(R)-tert-butyl 2-((S)-amino(3-fluoro-4-methoxyphenyl)methyl)pyrrolidine-1-carboxylate; In dichloromethane;

Downstream raw materials:

C₃₁H₃₇F₂N₅O₅

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