Pentanedioic acid bis-{[3-(2-amino-4-bromo-phenylsulfanyl)-phenyl]-amide}

Base Information

• Chemical Name: Pentanedioic acid bis-{[3-(2-amino-4-bromo-phenylsulfanyl)-phenyl]-amide}
• CAS No.: 188059-04-3
• Molecular Formula: C₂₉H₂₆Br₂N₄O₂S₂
• Molecular Weight: 686.491
• Mol file: 188059-04-3.mol

Synonyms:Pentanedioic acid bis-{[3-(2-amino-4-bromo-phenylsulfanyl)-phenyl]-amide}

Chemical Property of Pentanedioic acid bis-{[3-(2-amino-4-bromo-phenylsulfanyl)-phenyl]-amide}

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Pentanedioic acid bis-{[3-(2-amino-4-bromo-phenylsulfanyl)-phenyl]-amide}

There total 5 articles about Pentanedioic acid bis-{[3-(2-amino-4-bromo-phenylsulfanyl)-phenyl]-amide} which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Pentanedioic acid bis-{[3-(4-bromo-2-nitro-phenylsulfanyl)-phenyl]-amide} (188059-03-2) → Pentanedioic acid bis-{[3-(2-amino-4-bromo-phenylsulfanyl)-phenyl]-amide} (188059-04-3)

Guidance literature:

With hydrogenchloride; iron; In ethanol; for 1h; Heating;

DOI:10.1016/S0223-5234(97)84360-7

Reference yield:

gloutaric dichloride (2873-74-7) → Pentanedioic acid bis-{[3-(2-amino-4-bromo-phenylsulfanyl)-phenyl]-amide} (188059-04-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / pyridine / 1) 0 deg C, 1 h; 2) rt, 7 h

2: 100 percent / aq. HCl, iron powder / ethanol / 1 h / Heating

With pyridine; hydrogenchloride; iron; In ethanol;

DOI:10.1016/S0223-5234(97)84360-7

Reference yield:

1,4-dibromo-2-nitrobenzene (3460-18-2) → Pentanedioic acid bis-{[3-(2-amino-4-bromo-phenylsulfanyl)-phenyl]-amide} (188059-04-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 84 percent / sodium acetate / ethanol / 36 h / Heating

2: 95 percent / pyridine / 1) 0 deg C, 1 h; 2) rt, 7 h

3: 100 percent / aq. HCl, iron powder / ethanol / 1 h / Heating

With pyridine; hydrogenchloride; sodium acetate; iron; In ethanol;

DOI:10.1016/S0223-5234(97)84360-7

upstream raw materials:

Pentanedioic acid bis-{[3-(4-bromo-2-nitro-phenylsulfanyl)-phenyl]-amide}

gloutaric dichloride

1,4-dibromo-2-nitrobenzene

3-aminothiophenol

Downstream raw materials:

Pentanedioic acid bis-[(3-{4-bromo-2-[3-(4-methyl-piperazin-1-yl)-propionylamino]-phenylsulfanyl}-phenyl)-amide]