(1R/1S,S_S)-1-<3-(p-tolylsulfinyl)-2-furyl>-trans-crotyl alcohol

Base Information

• Chemical Name: (1R/1S,S_S)-1-<3-(p-tolylsulfinyl)-2-furyl>-trans-crotyl alcohol
• CAS No.: 211931-21-4
• Molecular Formula: C₁₅H₁₆O₃S
• Molecular Weight: 276.356
• Mol file: 211931-21-4.mol

Synonyms:(1R/1S,S_S)-1-<3-(p-tolylsulfinyl)-2-furyl>-trans-crotyl alcohol

Chemical Property of (1R/1S,S_S)-1-<3-(p-tolylsulfinyl)-2-furyl>-trans-crotyl alcohol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1R/1S,S_S)-1-<3-(p-tolylsulfinyl)-2-furyl>-trans-crotyl alcohol

There total 2 articles about (1R/1S,S_S)-1-<3-(p-tolylsulfinyl)-2-furyl>-trans-crotyl alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trans-Crotonaldehyde (123-73-9,4170-30-3) + 3-((S)-Toluene-4-sulfinyl)-furan-2-carbaldehyde (159812-85-8) → (1R/1S,SS)-1-<3-(p-tolylsulfinyl)-2-furyl>-trans-crotyl alcohol (211931-21-4)

Guidance literature:

With lithium diisopropyl amide; In tetrahydrofuran; hexane;

DOI:10.1039/P19960000759

Reference yield:

trans-Crotonaldehyde (123-73-9,4170-30-3) + (+)-(SS)-3-(p-tolylsulfinyl)furan (143810-75-7) → (1R/1S,SS)-1-<3-(p-tolylsulfinyl)-2-furyl>-trans-crotyl alcohol (211931-21-4)

Guidance literature:

With lithium diisopropyl amide; Yield given; Multistep reaction; 1.) THF, hexane, -78 deg C, 2.) THF, hexane;

DOI:10.1248/cpb.46.1078

Reference yield: 73.0%

(1R/1S,SS)-1-<3-(p-tolylsulfinyl)-2-furyl>-trans-crotyl alcohol (211931-21-4) → (SS)-2-trans-crotonyl-3-(p-tolylsulfinyl)furan (177547-57-8)

Guidance literature:

With manganese(IV) oxide; In chloroform; for 0.5h; Ambient temperature;

DOI:10.1248/cpb.46.1078

upstream raw materials:

trans-Crotonaldehyde

3-((S)-Toluene-4-sulfinyl)-furan-2-carbaldehyde

(+)-(SS)-3-(p-tolylsulfinyl)furan

Downstream raw materials:

(S_S)-2-trans-crotonyl-3-(p-tolylsulfinyl)furan

(1S,2S,3R,4R,S_S)-2-<3-(p-tolylsulfinyl)-2-furoyl>-3-methylbicyclo<2.2.1>hept-5-ene

(1R,2R,3R,4S,S_S)-2-<3-(p-tolylsulfinyl)-2-furoyl>-3-methylbicyclo<2.2.1>heptane