Technology Process of 2,5-dimethyl-N-phenylpyrazolo<1,5-a>pyrimidine-3-carboxamide
There total 5 articles about 2,5-dimethyl-N-phenylpyrazolo<1,5-a>pyrimidine-3-carboxamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen; sodium acetate;
palladium on activated charcoal;
In
acetic acid;
for 24h;
under 1520 Torr;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 50 percent / acetic anhydride / 120 - 130 °C
2: 77 percent / hydrazine hydrate / 1 h / Heating
3: 93 percent / glacial acetic acid / 1 h / Heating
4: 67 percent / POCl3, N,N-dimethylaniline / 1 h / Heating
5: 77 percent / H2, CH3COONa / 5percent Pd/C / acetic acid / 24 h / 1520 Torr / Ambient temperature
With
hydrogen; sodium acetate; acetic anhydride; hydrazine hydrate; acetic acid; N,N-dimethyl-aniline; trichlorophosphate;
palladium on activated charcoal;
In
acetic acid;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 77 percent / hydrazine hydrate / 1 h / Heating
2: 93 percent / glacial acetic acid / 1 h / Heating
3: 67 percent / POCl3, N,N-dimethylaniline / 1 h / Heating
4: 77 percent / H2, CH3COONa / 5percent Pd/C / acetic acid / 24 h / 1520 Torr / Ambient temperature
With
hydrogen; sodium acetate; hydrazine hydrate; acetic acid; N,N-dimethyl-aniline; trichlorophosphate;
palladium on activated charcoal;
In
acetic acid;
