2-isopropyl-1-[4-{3-[N-methyl-N-(3,5-dimethoxy-β-phenethyl)amino]propyloxy}benzenesulphonyl]indolizine

Base Information

Chemical Name:2-isopropyl-1-[4-{3-[N-methyl-N-(3,5-dimethoxy-β-phenethyl)amino]propyloxy}benzenesulphonyl]indolizine
CAS No.:133675-55-5
Molecular Formula:C₃₁H₃₈N₂O₅S
Molecular Weight:550.719
Hs Code.:

Synonyms:2-isopropyl-1-[4-{3-[N-methyl-N-(3,5-dimethoxy-β-phenethyl)amino]propyloxy}benzenesulphonyl]indolizine

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Chemical Property of 2-isopropyl-1-[4-{3-[N-methyl-N-(3,5-dimethoxy-β-phenethyl)amino]propyloxy}benzenesulphonyl]indolizine

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Technology Process of 2-isopropyl-1-[4-{3-[N-methyl-N-(3,5-dimethoxy-β-phenethyl)amino]propyloxy}benzenesulphonyl]indolizine

There total 6 articles about 2-isopropyl-1-[4-{3-[N-methyl-N-(3,5-dimethoxy-β-phenethyl)amino]propyloxy}benzenesulphonyl]indolizine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4377-33-7
2-chloromethylpyridine

: 133675-55-5
2-isopropyl-1-[4-{3-[N-methyl-N-(3,5-dimethoxy-β-phenethyl)amino]propyloxy}benzenesulphonyl]indolizine

Guidance literature:: Multi-step reaction with 5 steps

1: AcONa / butan-1-ol

2: 70 percent / K₂CO₃ / butan-2-one / 2 h / Heating

3: 90 percent / aq. NaOH / ethanol / 24 h / Heating

4: 85 percent / K₂CO₃ / butan-2-one / 24 h / Heating

5: Et₃N / toluene / 24 h / Heating

With sodium hydroxide; sodium acetate; potassium carbonate; triethylamine; In ethanol; toluene; butanone; butan-1-ol;
DOI:10.1021/jm00084a002

Reference yield:

: 114432-21-2
2-isopropyl-1-<(4-hydroxyphenyl)sulfonyl>indolizine

: 133675-55-5
2-isopropyl-1-[4-{3-[N-methyl-N-(3,5-dimethoxy-β-phenethyl)amino]propyloxy}benzenesulphonyl]indolizine

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / K₂CO₃ / butan-2-one / 24 h / Heating

2: Et₃N / toluene / 24 h / Heating

With potassium carbonate; triethylamine; In toluene; butanone;
DOI:10.1021/jm00084a002

Reference yield:

: 133804-17-8
5-tosyloxyphenyl 2-methylpyridyl sulfone

: 133675-55-5
2-isopropyl-1-[4-{3-[N-methyl-N-(3,5-dimethoxy-β-phenethyl)amino]propyloxy}benzenesulphonyl]indolizine

Guidance literature:: Multi-step reaction with 4 steps

1: 70 percent / K₂CO₃ / butan-2-one / 2 h / Heating

2: 90 percent / aq. NaOH / ethanol / 24 h / Heating

3: 85 percent / K₂CO₃ / butan-2-one / 24 h / Heating

4: Et₃N / toluene / 24 h / Heating

With sodium hydroxide; potassium carbonate; triethylamine; In ethanol; toluene; butanone;
DOI:10.1021/jm00084a002