DL-Amino-{4-[(3-isopropyl-1H-indol-5-yl)oxy]-3,5-bis-trifluoromethylphenyl}-acetic acid

Base Information

Chemical Name:DL-Amino-{4-[(3-isopropyl-1H-indol-5-yl)oxy]-3,5-bis-trifluoromethylphenyl}-acetic acid
CAS No.:439612-30-3
Molecular Formula:C₂₁H₁₈F₆N₂O₃
Molecular Weight:460.376
Hs Code.:

Synonyms:DL-Amino-{4-[(3-isopropyl-1H-indol-5-yl)oxy]-3,5-bis-trifluoromethylphenyl}-acetic acid

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Chemical Property of DL-Amino-{4-[(3-isopropyl-1H-indol-5-yl)oxy]-3,5-bis-trifluoromethylphenyl}-acetic acid

Chemical Property:

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Technology Process of DL-Amino-{4-[(3-isopropyl-1H-indol-5-yl)oxy]-3,5-bis-trifluoromethylphenyl}-acetic acid

There total 4 articles about DL-Amino-{4-[(3-isopropyl-1H-indol-5-yl)oxy]-3,5-bis-trifluoromethylphenyl}-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 439612-29-0
5-{4-[(3-Isopropyl-1H-indol-5-yl)oxy]-3,5-bis-trifluoromethylphenyl}-imidazolidin-2,4-dione

: 439612-30-3
DL-Amino-{4-[(3-isopropyl-1H-indol-5-yl)oxy]-3,5-bis-trifluoromethylphenyl}-acetic acid

Guidance literature:: With lithium hydroxide; In water;

Reference yield:

: 439612-63-2
3,5-bis(trifluoromethyl)-4-chlorobenzaldehyde

: 439612-30-3
DL-Amino-{4-[(3-isopropyl-1H-indol-5-yl)oxy]-3,5-bis-trifluoromethylphenyl}-acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / dimethyl sulfoxide; ethyl acetate

2: ammonium carbonate / methanol; ethanol; dichloromethane; water

3: lithium hydroxide / water

With ammonium carbonate; lithium hydroxide; potassium carbonate; In methanol; ethanol; dichloromethane; water; dimethyl sulfoxide; ethyl acetate;

Reference yield:

: 361436-24-0
3-isopropyl-1H-indol-5-ol

: 439612-30-3
DL-Amino-{4-[(3-isopropyl-1H-indol-5-yl)oxy]-3,5-bis-trifluoromethylphenyl}-acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / dimethyl sulfoxide; ethyl acetate

2: ammonium carbonate / methanol; ethanol; dichloromethane; water

3: lithium hydroxide / water

With ammonium carbonate; lithium hydroxide; potassium carbonate; In methanol; ethanol; dichloromethane; water; dimethyl sulfoxide; ethyl acetate;