2H-1b,4-Ethanopentaleno[1,2-b]oxirene, hexahydro-, (1a-alpha-,1b-bta-,4-bta-,4a-alpha-,5a-alpha-)- (9CI)

Base Information

• Chemical Name: 2H-1b,4-Ethanopentaleno[1,2-b]oxirene, hexahydro-, (1a-alpha-,1b-bta-,4-bta-,4a-alpha-,5a-alpha-)- (9CI)
• CAS No.: 117221-80-4
• Molecular Formula: C₁₀H₁₄O
• Molecular Weight: 150.221
• Mol file: 117221-80-4.mol

Synonyms:2H-1b,4-Ethanopentaleno[1,2-b]oxirene, hexahydro-, (1a-alpha-,1b-bta-,4-bta-,4a-alpha-,5a-alpha-)- (9CI)

Chemical Property of 2H-1b,4-Ethanopentaleno[1,2-b]oxirene, hexahydro-, (1a-alpha-,1b-bta-,4-bta-,4a-alpha-,5a-alpha-)- (9CI)

Chemical Property:

• Boiling Point: 225.1±8.0 °C(Predicted)
• Density: 1.17±0.1 g/cm3(Predicted)

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2H-1b,4-Ethanopentaleno[1,2-b]oxirene, hexahydro-, (1a-alpha-,1b-bta-,4-bta-,4a-alpha-,5a-alpha-)- (9CI)

There total 2 articles about 2H-1b,4-Ethanopentaleno[1,2-b]oxirene, hexahydro-, (1a-alpha-,1b-bta-,4-bta-,4a-alpha-,5a-alpha-)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tricyclo<4.2.2.01,5>dec-4-ene (72378-15-5) → 2C(9),3(C9)-epoxytricyclo<4.2.2.01,5>decane (117221-80-4)

Guidance literature:

Multi-step reaction with 5 steps

1: 50.5 percent / CrO₃, 3,5-dimethylpyrazole / CH₂Cl₂ / 1.) -20 deg C, 10 h, 2.) warming up to 10 deg C, 13 h

2: 88 percent / 10percent Pd/C, H₂ / ethanol / 3.5 h

3: 90.5 percent / LiAlH₄ / diethyl ether / 2 h / Ambient temperature

4: 100 percent / Et₃N / CH₂Cl₂ / 1.75 h / 0 °C

5: 1.) t-BuOK, 2.) 90percent m-chloroperbenzoic acid / 1.) DMSO, room temperature, 1 h, 2.) CH₂Cl₂, 0 deg C, 15 h

With 3,5-dimethyl-1H-pyrazole; chromium(VI) oxide; palladium on activated charcoal; lithium aluminium tetrahydride; potassium tert-butylate; hydrogen; triethylamine; 3-chloro-benzenecarboperoxoic acid; In diethyl ether; ethanol; dichloromethane;

DOI:10.1002/hlca.19880710115

Reference yield:

tricyclo<4.2.2.01,5>decan-3C(8)-yl methanesulfonate → 2C(9),3(C9)-epoxytricyclo<4.2.2.01,5>decane (117221-80-4) + 3C(9),4C(9)-epoxytricyclo<4.2.2.01,5>decane (117221-81-5)

Guidance literature:

With potassium tert-butylate; 3-chloro-benzenecarboperoxoic acid; Yield given. Multistep reaction. Yields of byproduct given; 1.) DMSO, room temperature, 1 h, 2.) CH₂Cl₂, 0 deg C, 15 h;

DOI:10.1002/hlca.19880710115

upstream raw materials:

tricyclo<4.2.2.0^1,5>dec-4-ene