tert-butyl (2S)-3-(4-(allyloxy)phenyl)-2-((2S)-2-((2S,4S)-4-azido-1-((2S)-2-((2S)-2-((tert-butoxycarbonyl)(methyl)amino)propanamido)-3,3-dimethylbutanoyl)pyrrolidine-2-carboxamido)-3-(naphthalen-2-yl)propanamido)propanoate

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Chemical Name:tert-butyl (2S)-3-(4-(allyloxy)phenyl)-2-((2S)-2-((2S,4S)-4-azido-1-((2S)-2-((2S)-2-((tert-butoxycarbonyl)(methyl)amino)propanamido)-3,3-dimethylbutanoyl)pyrrolidine-2-carboxamido)-3-(naphthalen-2-yl)propanamido)propanoate
CAS No.:1609554-63-3
Molecular Formula:C₄₉H₆₆N₈O₉
Molecular Weight:911.111
Hs Code.:

tert-butyl (2S)-3-(4-(allyloxy)phenyl)-2-((2S)-2-((2S,4S)-4-azido-1-((2S)-2-((2S)-2-((tert-butoxycarbonyl)(methyl)amino)propanamido)-3,3-dimethylbutanoyl)pyrrolidine-2-carboxamido)-3-(naphthalen-2-yl)propanamido)propanoate

Synonyms:tert-butyl (2S)-3-(4-(allyloxy)phenyl)-2-((2S)-2-((2S,4S)-4-azido-1-((2S)-2-((2S)-2-((tert-butoxycarbonyl)(methyl)amino)propanamido)-3,3-dimethylbutanoyl)pyrrolidine-2-carboxamido)-3-(naphthalen-2-yl)propanamido)propanoate

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Chemical Property of tert-butyl (2S)-3-(4-(allyloxy)phenyl)-2-((2S)-2-((2S,4S)-4-azido-1-((2S)-2-((2S)-2-((tert-butoxycarbonyl)(methyl)amino)propanamido)-3,3-dimethylbutanoyl)pyrrolidine-2-carboxamido)-3-(naphthalen-2-yl)propanamido)propanoate

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Technology Process of tert-butyl (2S)-3-(4-(allyloxy)phenyl)-2-((2S)-2-((2S,4S)-4-azido-1-((2S)-2-((2S)-2-((tert-butoxycarbonyl)(methyl)amino)propanamido)-3,3-dimethylbutanoyl)pyrrolidine-2-carboxamido)-3-(naphthalen-2-yl)propanamido)propanoate

There total 12 articles about tert-butyl (2S)-3-(4-(allyloxy)phenyl)-2-((2S)-2-((2S,4S)-4-azido-1-((2S)-2-((2S)-2-((tert-butoxycarbonyl)(methyl)amino)propanamido)-3,3-dimethylbutanoyl)pyrrolidine-2-carboxamido)-3-(naphthalen-2-yl)propanamido)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1434125-68-4
(2S)-2-((2S,4S)-4-azido-1-((2S)-2-((2S)-2-((tert-butoxycarbonyl)(methyl)amino)propanamido)-3,3-dimethylbutanoyl)pyrrolidine-2-carboxamido)-3-(naphthalen-2-yl)propanoic acid

: (S)-tert-Butyl 3-(4-(allyloxy)phenyl)-2-((tert-butoxycarbonyl)amino) propanoate

: 1609554-63-3
tert-butyl (2S)-3-(4-(allyloxy)phenyl)-2-((2S)-2-((2S,4S)-4-azido-1-((2S)-2-((2S)-2-((tert-butoxycarbonyl)(methyl)amino)propanamido)-3,3-dimethylbutanoyl)pyrrolidine-2-carboxamido)-3-(naphthalen-2-yl)propanamido)propanoate

Guidance literature:: With 4-methyl-morpholine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide; at 20 ℃; for 12h; Inert atmosphere;

Reference yield: 98.0%

: 1434125-68-4
(2S)-2-((2S,4S)-4-azido-1-((2S)-2-((2S)-2-((tert-butoxycarbonyl)(methyl)amino)propanamido)-3,3-dimethylbutanoyl)pyrrolidine-2-carboxamido)-3-(naphthalen-2-yl)propanoic acid

: 1609554-62-2
tert-butyl (S)-3-(4-(allyloxy)phenyl)-2-aminopropanoate

: 1609554-63-3
tert-butyl (2S)-3-(4-(allyloxy)phenyl)-2-((2S)-2-((2S,4S)-4-azido-1-((2S)-2-((2S)-2-((tert-butoxycarbonyl)(methyl)amino)propanamido)-3,3-dimethylbutanoyl)pyrrolidine-2-carboxamido)-3-(naphthalen-2-yl)propanamido)propanoate

Guidance literature:: With 4-methyl-morpholine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide; at 20 ℃; for 12h; Inert atmosphere;
DOI:10.1021/acsmedchemlett.5b00091

Reference yield: 98.0%

: 1609554-63-3
tert-butyl (2S)-3-(4-(allyloxy)phenyl)-2-((2S)-2-((2S,4S)-4-azido-1-((2S)-2-((2S)-2-((tert-butoxycarbonyl)(methyl)amino)propanamido)-3,3-dimethylbutanoyl)pyrrolidine-2-carboxamido)-3-(naphthalen-2-yl)propanamido)propanoate

Guidance literature:: With N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide;