Cyclopentanecarboxamide, 3-(hydroxymethyl)-, cis- (9CI)

Base Information

Chemical Name:Cyclopentanecarboxamide, 3-(hydroxymethyl)-, cis- (9CI)
CAS No.:116940-85-3
Molecular Formula:C₇H₁₃NO₂
Molecular Weight:143.186
Hs Code.:
Mol file:116940-85-3.mol

Synonyms:Cyclopentanecarboxamide,3-(hydroxymethyl)-, cis- (9CI); Cyclopentanecarboxamide, 3-(hydroxymethyl)-, cis-(?à)-

Suppliers and Price of Cyclopentanecarboxamide, 3-(hydroxymethyl)-, cis- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of Cyclopentanecarboxamide, 3-(hydroxymethyl)-, cis- (9CI)

Chemical Property:

PSA：63.32000
LogP:0.58060

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Cyclopentanecarboxamide, 3-(hydroxymethyl)-, cis- (9CI)

There total 5 articles about Cyclopentanecarboxamide, 3-(hydroxymethyl)-, cis- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.7%

: 116595-43-8,116940-84-2
(+/-)-cis methyl 3-(aminocarbonyl)cyclopentanecarboxylate

: 116940-85-3
(+/-)-cis-3-(hydroxymethyl)cyclopentanecarboxamide

Guidance literature:: With lithium borohydride; In tetrahydrofuran; for 2h; Heating;
DOI:10.1139/v88-009

Reference yield:

: 6054-16-6
cis-1,3-cyclopentanedicarboxylic acid anhydride

: 116940-85-3
(+/-)-cis-3-(hydroxymethyl)cyclopentanecarboxamide

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) r.t., 19 h; 2.) 2 deg C, 12 days

2: 26.2 g / thionyl chloride, pyridine, DMF / benzene / 2 h / Heating

3: 16.01 g / NH₃ / benzene / 0.5 h

4: 85.7 percent / lithium borohydride / tetrahydrofuran / 2 h / Heating

With pyridine; lithium borohydride; thionyl chloride; ammonia; N,N-dimethyl-formamide; In tetrahydrofuran; benzene;
DOI:10.1139/v88-009

Reference yield:

: 876-05-1,826-02-8
cis-1,3-cyclopentanedicarboxylic acid

: 116940-85-3
(+/-)-cis-3-(hydroxymethyl)cyclopentanecarboxamide

Guidance literature:: Multi-step reaction with 5 steps

1: 79 percent / acetic anhydride / 0.5 h / Heating

2: 1.) r.t., 19 h; 2.) 2 deg C, 12 days

3: 26.2 g / thionyl chloride, pyridine, DMF / benzene / 2 h / Heating

4: 16.01 g / NH₃ / benzene / 0.5 h

5: 85.7 percent / lithium borohydride / tetrahydrofuran / 2 h / Heating

With pyridine; lithium borohydride; thionyl chloride; ammonia; N,N-dimethyl-formamide; In tetrahydrofuran; acetic anhydride; benzene;
DOI:10.1139/v88-009