ethyl [9-{10-(4-(t-butyl)-2,6-dimethylphenyl)}anthryl](4-bromo-2,6-dimethylphenyl)methylcarbamate

Base Information

• Chemical Name: ethyl [9-{10-(4-(t-butyl)-2,6-dimethylphenyl)}anthryl](4-bromo-2,6-dimethylphenyl)methylcarbamate
• CAS No.: 666257-66-5
• Molecular Formula: C₃₈H₄₀BrNO₂
• Molecular Weight: 622.645
• Mol file: 666257-66-5.mol

Synonyms:ethyl [9-{10-(4-(t-butyl)-2,6-dimethylphenyl)}anthryl](4-bromo-2,6-dimethylphenyl)methylcarbamate

Chemical Property of ethyl [9-{10-(4-(t-butyl)-2,6-dimethylphenyl)}anthryl](4-bromo-2,6-dimethylphenyl)methylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl [9-{10-(4-(t-butyl)-2,6-dimethylphenyl)}anthryl](4-bromo-2,6-dimethylphenyl)methylcarbamate

There total 6 articles about ethyl [9-{10-(4-(t-butyl)-2,6-dimethylphenyl)}anthryl](4-bromo-2,6-dimethylphenyl)methylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

urethane (51-79-6) + [9-{10-(4-tert-butyl-2,6-dimethylphenyl)anthryl}](4-bromo-2,6-dimethylphenyl)chloromethane (666257-65-4) → ethyl [9-{10-(4-(t-butyl)-2,6-dimethylphenyl)}anthryl](4-bromo-2,6-dimethylphenyl)methylcarbamate (666257-66-5)

Guidance literature:

With silver tetrafluoroborate; In 1,4-dioxane; Heating;

DOI:10.1021/ja038450p DOI:10.1021/jo0494026

Reference yield:

anthracen-9(10H)-one (90-44-8) → ethyl [9-{10-(4-(t-butyl)-2,6-dimethylphenyl)}anthryl](4-bromo-2,6-dimethylphenyl)methylcarbamate (666257-66-5)

Guidance literature:

Multi-step reaction with 5 steps

1.1: tBuLi / diethyl ether; pentane / -78 - 20 °C

1.2: 44 percent / toluene; diethyl ether; pentane / Heating

2.1: 89 percent / bromine / CCl₄ / 20 °C

3.1: nBuLi / diethyl ether; hexane / 3 h / 0 °C

3.2: 74 percent / tetrahydrofuran; diethyl ether; hexane / 20 °C

4.1: 97 percent / HCl / benzene / 1 h / 5 °C

5.1: 75 percent / silver tetrafluoroborate / dioxane / Heating

With hydrogenchloride; silver tetrafluoroborate; n-butyllithium; bromine; tert.-butyl lithium; In 1,4-dioxane; tetrachloromethane; diethyl ether; hexane; pentane; benzene;

DOI:10.1021/jo0494026

Reference yield:

4-t-butyl-2,6-dimethylbromobenzene (5345-05-1) → ethyl [9-{10-(4-(t-butyl)-2,6-dimethylphenyl)}anthryl](4-bromo-2,6-dimethylphenyl)methylcarbamate (666257-66-5)

Guidance literature:

Multi-step reaction with 5 steps

1.1: tBuLi / diethyl ether; pentane / -78 - 20 °C

1.2: 44 percent / toluene; diethyl ether; pentane / Heating

2.1: 89 percent / bromine / CCl₄ / 20 °C

3.1: nBuLi / diethyl ether; hexane / 3 h / 0 °C

3.2: 74 percent / tetrahydrofuran; diethyl ether; hexane / 20 °C

4.1: 97 percent / HCl / benzene / 1 h / 5 °C

5.1: 75 percent / silver tetrafluoroborate / dioxane / Heating

With hydrogenchloride; silver tetrafluoroborate; n-butyllithium; bromine; tert.-butyl lithium; In 1,4-dioxane; tetrachloromethane; diethyl ether; hexane; pentane; benzene;

DOI:10.1021/jo0494026

upstream raw materials:

urethane

[9-{10-(4-tert-butyl-2,6-dimethylphenyl)anthryl}](4-bromo-2,6-dimethylphenyl)chloromethane

4-t-butyl-2,6-dimethylbromobenzene

anthracen-9(10H)-one

Downstream raw materials:

9-(4-tert-butyl-2,6-dimethyl-phenyl)-10-[diazo-(4-ethynyl-2,6-dimethyl-phenyl)-methyl]-anthracene

[9-{10-(4-(t-butyl)-2,6-dimethylphenyl)}anthryl][2,6-dimethyl-4-(trimethylsilylethynyl)phenyl]diazomethane

2,5-bis(3,5-dimethyl-4-[9-{10-(4-(t-butyl)-2,6-dimethylphenyl)}anthryl]diazomethylphenyl)thiophene

1,4-bis(3,5-dimethyl-4-[9-{10-(4-(t-butyl)-2,6-dimethylphenyl)}anthryl]diazomethylphenyl)butadiyne